CACNB2 Antibodies

AND CACNB2 ELISA kits, CACNB2 Proteins

Many biological assays use antibodies to detect CACNB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNB2 antibodies...

We validate the specificity of these antibodies to CACNB2 by testing them on tissues known to express CACNB2 positively and negatively. Browse below to find the CACNB2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CACNB2 Infographic by Boster Bio

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CACNB2 (NM_000724) Human Over-expression Lysate

CACNB2 Human Over-expression Lysates NM_000724

Human

$960
Cat # LS000783
20 µg, 100 µg

CACNB2 Overview

Facts about Voltage-dependent L-type calcium channel subunit beta-2.

CACNB2 3D structure. Source: alphafold

Voltage-dependent L-type calcium channel subunit beta-2 (CACNB2)

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. .

Gene Information

Human
Gene Name:	CACNB2
Uniprot:	Q08289
Entrez:	783

Family

Belongs to:

calcium channel beta subunit family

Alternative Names

CAB2; CACNLB2; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CAVB2; FLJ23743; Lambert-Eaton myasthenic syndrome antigen B; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; voltage-dependent L-type calcium channel subunit beta-2

Molecular Weight

Mass (kDA):
73.581 kDA

Genomic Context


Human

Location:	10p12.33-p12.31
Sequence:	10; NC_000010.11 (18140424..18545881)

Tissue Specificity

Expressed in all tissues.

Subcellular Localizations

Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.

Diseases

Brugada Syndrome (disorder)
Cardiac Arrhythmia
Hypertensive Disease
Ventricular Fibrillation
Cardiac Fibrillation
Sudden Cardiac Death
Syncope
Heart Diseases
Cardiac Death
Cardiovascular Diseases
Nervousness
Tachycardia, Ventricular

Disease Of Adrenal Medulla
Channelopathies
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Bradycardia
Obesity
Neonatal Maladjustment Syndrome

Interacting Proteins

CACNA1C

Pathways

Localization
Exocytosis
Transport
Cardiac Conduction
Pathogenesis
Receptor-mediated Endocytosis
Cell Proliferation
Cellular Homeostasis
Insulin Secretion
Ion Transport
Synaptic Transmission
Endocytosis

Neutrophil Activation
Membrane Depolarization
Dna Amplification
Translation
Innervation
Secretion

PTMs

Phosphorylation

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNB2

References

PMID: 8494331 by Rosenfeld M.R., et al. Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.

PMID: 9254841 by Taviaux S., et al. Assignment of human genes for beta 2 and beta 4 subunits of voltage- dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.