CACNB3 Antibodies

AND CACNB3 ELISA kits, CACNB3 Proteins

Many biological assays use antibodies to detect CACNB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNB3 antibodies...

We validate the specificity of these antibodies to CACNB3 by testing them on tissues known to express CACNB3 positively and negatively. Browse below to find the CACNB3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CACNB3 Infographic by Boster Bio

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CACNB3 Overview

Facts about Voltage-dependent L-type calcium channel subunit beta-3.

CACNB3 3D structure. Source: alphafold

Voltage-dependent L-type calcium channel subunit beta-3 (CACNB3)

Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8119293). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).

Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). .

Gene Information

Human
Gene Name:	CACNB3
Uniprot:	P54284
Entrez:	784

Family

Belongs to:

calcium channel beta subunit family

Alternative Names

CAB3; CACNLB3; Calcium channel voltage-dependent subunit beta 3; calcium channel, voltage-dependent, beta 3 subunit; voltage-dependent L-type calcium channel subunit beta-3

Molecular Weight

Mass (kDA):
54.532 kDA

Genomic Context


Human

Location:	12q13.12
Sequence:	12; NC_000012.12 (48814432..48828941)

Tissue Specificity

Expressed mostly in brain, colon and ovary.

Subcellular Localizations

Cytoplasm.

Diseases

Atrophy
Disease Of Adrenal Medulla
Brain Ischemia
Weakness
Malignant Neoplasm Of Lung
Venous Thrombosis
Memory Disorders
Malignant Neoplasms
Neoplasms
Nervousness
Cerebrovascular Accident
Pain

Cerebral Ischemia
Spinal Muscular Atrophy
Nerve Damage
Anxiety Disorders
Charcot-marie-tooth Disease
Ischemia

Interacting Proteins

CACNA1C

Pathways

Localization
Transport
Blood Coagulation
Cellular Homeostasis
Insulin Secretion
Immune Response
Synaptic Transmission
Response To Ischemia
Flight
Coagulation
Cell Death

Rna Processing
Hemostasis
Regulation Of Insulin Secretion
Exocytosis
Excretion
Secretion

PTMs

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNB3

References

PMID: 7557998 by Yamada Y., et al. The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.

PMID: 8119293 by Collin T., et al. Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit.