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- Table of Contents
Calnexin Antibodies
AND CANX ELISA kits, Calnexin Proteins
Many biological assays use antibodies to detect Calnexin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calnexin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calnexin antibodies...
Designing a Western blot for Calnexin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CANX Western Blot GuideCANX Infographic by Boster Bio
All CANX Products
Product
Figures
Specificity
Applications
Price
Anti-Calnexin/CANX Antibody Picoband®
4 Citations
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03372-2
100 μg/vial
Cat # A03372-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03372-2
100 μg/vial
Cat # M03372-2
100 μg/vial
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03372-1
100 μl
Cat # M03372-1
100 μl
Human, Mouse, Rat
ELISA
$540
Cat # EKC2058
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2058
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1075
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1075
1 kit, containing one 96-well plate and all necessary reagents
CANX Overview
Facts about Calnexin.
Calnexin (CANX)
Calcium-binding protein which interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It could behave in helping protein assembly or at the retention within the ER of unassembled protein subunits.
It seems to play a significant role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes which escape the ER of immature thymocytes, it may be a signaling complex regulating thymocyte maturation.
Gene Information
| Human | |
|---|---|
| Gene Name: | CANX |
| Uniprot: | P27824 |
| Entrez: | 821 |
Family
| Belongs to: |
|---|
| calreticulin family |
Alternative Names
calnexin; CNX; IP90FLJ26570; Major histocompatibility complex class I antigen-binding protein p88; P90
Molecular Weight
Mass (kDA):
67.568 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q35.3 |
| Sequence: | 5; NC_000005.10 (179678646..179731641) |
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232).
Diseases
- Endoplasmic Reticulum Stress
- Carcinoma
- Malignant Neoplasms
- Neoplasms
- Retinal Degeneration
- Hepatitis B
- Hypoxia
- Lung Diseases
- Infertility
- Malignant Neoplasm Of Lung
- Edema
- Sarcoidosis
Interacting Proteins
- ABCA1
- CFTR
- CHST15
- NDRG1
- OPRD1
- RPL12
- SEC61A1
- SSR1
Pathways
- Fertilization
- Regeneration
- Reverse Transcription
- Cell Proliferation
- Translation
- Cell Death
- Sperm Capacitation
- Mating
PTMs
- Acetylation
- Disulfide bond
- Lipoprotein
Research Areas
- Unfolded Protein Response
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CANX
bosterbio.com/bosterbio-gene-info-cards/CANX
References
PMID: 8486646 by David V., et al. Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin).
PMID: 8136357 by Tjoelker L.W., et al. Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5.
6 Publications of Boster Calnexin Antibodies & ELISA Kits
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2011.20.023, Calcineurin is involved in cardioprotection induced by ischemic postconditioning...
- PubMed ID: 10.1186/s13046-021-01979-7, Hypoxic tumor-derived exosomal miR-31-5p promotes lung adenocarcinoma metastasis...
- PubMed ID: 10.1021/acsnano.1c04514, Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Atte...
- PubMed ID: 10.1007/s10529-021-03148-4, Serum-derived exosomes accelerate scald wound healing in mice by optimizing cell...
- PubMed ID: 34074322, Yu F,Liang M,Huang Y,Wu W,Zheng B,Chen C.Hypoxic tumor-derived exosomal miR-31-5...
- PubMed ID: 34014413, Li Y,Yu Y,Xie Z,Ye X,Liu X,Xu B,Mao J.Serum-derived exosomes accelerate scald wo...
*More publications can be found for each product on its corresponding product page