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- Table of Contents
Calpain-11 Antibodies
AND CAPN11 ELISA kits, Calpain-11 Proteins
Many biological assays use antibodies to detect Calpain-11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calpain-11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calpain-11 antibodies...
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CAPN11 Infographic by Boster Bio
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CAPN11 Overview
Facts about Calpain-11.
Calpain-11 (CAPN11)
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CAPN11 |
| Uniprot: | Q9UMQ6 |
| Entrez: | 11131 |
Family
| Belongs to: |
|---|
| peptidase C2 family |
Alternative Names
Calcium-activated neutral proteinase 11; calpain 11; calpain11; calpain-11; CANP 11; EC 3.4.22; EC 3.4.22.-; EC 3.4.22.52; EC 3.4.22.54
Molecular Weight
Mass (kDA):
84.423 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.1 |
| Sequence: | 6; NC_000006.12 (44158811..44184401) |
Tissue Specificity
Highest expression in testis.
Subcellular Localizations
Cytoplasmic vesicle, secretory vesicle, acrosome.
Diseases
- Malignant Tumor Of Cervix
- Carcinoma
Pathways
- Meiosis
- Pachytene
- Localization
- Spermatogenesis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPN11
bosterbio.com/bosterbio-gene-info-cards/CAPN11
References
PMID: 10409436 by Dear T.N., et al. CAPN11: a calpain with high mRNA levels in testis and located on chromosome 6.