Caspase-12 Antibodies

AND Casp12 ELISA kits, Caspase-12 Proteins

Many biological assays use antibodies to detect Caspase-12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-12 antibodies...

We validate the specificity of these antibodies to Caspase-12 by testing them on tissues known to express Casp12 positively and negatively. Browse below to find the Casp12 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: Casq1

Casp12 Infographic by Boster Bio

All Casp12 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Caspase-12/CASP12 Antibody Picoband®

10 Citations 7 Q&As

Anti-Caspase-12 antibody, PA2103, Western blottingAll lanes: Anti Caspase-12 (PA2103) at 0

Anti-Caspase-12 antibody, PA2103, IHC(P)IHC(P): Human Mammary Cancer Tissue

Anti-Caspase-12 antibody, PA2103, IHC(P)IHC(P): Human Lung Cancer Tissue

Human, Rat

IHC, WB

$370
Cat # PA2103
100 μg/vial

Casp12 Overview

Facts about Caspase-12.

Caspase-12 (Casp12)

Involved in the activation cascade of caspases responsible for apoptosis execution. .

Gene Information

Mouse
Gene Name:	Casp12
Uniprot:	O08736
Entrez:	12364

Family

Belongs to:

peptidase C14A family

Alternative Names

Apoptosis Related Cysteine Protease; CASP 12; CASP12; CASP12P1; Caspase 12 pseudogene 1; Caspase12; Caspase-12; UNQ9415

Molecular Weight

Mass (kDA):
47.854 kDA

Genomic Context


Mouse

Location:	9 A1\|9 2.46 cM
Sequence:	9;

Tissue Specificity

Mainly expressed in skeletal muscle and lung.

Diseases

Endoplasmic Reticulum Stress
Physiological Stress
Inflammation
Neurodegenerative Disorders
Malignant Neoplasms
Systemic Infection
Alzheimer's Disease
Neoplasms
Ischemia
Nerve Degeneration
Mitochondrial Damage
Neurotoxicity Syndromes
Infarction

Neuroblastoma
Sclerosis
Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Diabetes Mellitus
Cerebral Ischemia
Hypoxia

Pathways

Cell Death
Pathogenesis
Programmed Cell Death
Immune Response
Translation
Cell Proliferation
Proteolysis
Induction Of Apoptosis
Rna Interference
Transport
Cell Cycle
Cell Growth
Apoptotic Process

Secretion
Glycosylation
Protein Transport
Protein Folding
Tissue Homeostasis
Aging
Hypersensitivity

PTMs

Cleavage
Phosphorylation
Ubiquitination

Reduction
Glycosylation
Oxidation

Research Areas

Apoptosis
Cancer
Caspases

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Casp12

References

PMID: 9038361 by van de Craen M., et al. Characterization of seven murine caspase family members.

PMID: 11278723 by Yoneda T., et al. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2- dependent mechanism in response to the ER stress.

3 Publications of Boster Caspase-12 Antibodies & ELISA Kits

PubMed ID: 30651819, Bone marrow stromal cells improved functional recovery in spinal cord injury rat...
PubMed ID: 24013954, Zhao S, Xiong Z, Mao X, Meng D, Lei Q, Li Y, Deng P, Chen M, Tu M, Lu X, Yang G,...
PubMed ID: 21625440, Ding Y, Zou J, Li Z, Tian J, Abdelalim S, Du F, She R, Wang D, Tan C, Wang H, Ch...

*More publications can be found for each product on its corresponding product page