Castor1 Antibodies

AND Castor1 ELISA kits, Castor1 Proteins

Many biological assays use antibodies to detect Castor1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Castor1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Castor1 antibodies...

We validate the specificity of these antibodies to Castor1 by testing them on tissues known to express Castor1 positively and negatively. Browse below to find the Castor1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Castor1 Infographic by Boster Bio

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CASTOR1 (NM_001037666) Human Over-expression Lysate

Human

$628
Cat # LS652968
20 µg, 100 µg

Castor1 Overview

Facts about Cytosolic arginine sensor for mTORC1 subunit 1.

Cytosolic arginine sensor for mTORC1 subunit 1 (Castor1)

Functions as an intracellular arginine sensor inside the amino acid-sensing division of this TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1.

Binding of arginine into CASTOR1 allosterically disrupts the interaction of CASTOR1- containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway. .

Gene Information

Mouse
Gene Name:	Castor1
Uniprot:	Q9CWQ8
Entrez:	71962

Family

Belongs to:

GATS family

Alternative Names

Cytosolic arginine sensor for mTORC1 subunit 1

Molecular Weight

Mass (kDA):
36.575 kDA

Genomic Context


Mouse

Location:	11\|11 A1
Sequence:	11;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Castor1

References

PMID: 16141072 by Carninci P., et al. The transcriptional landscape of the mammalian genome.

PMID: 19468303 by Church D.M., et al. Lineage-specific biology revealed by a finished genome assembly of the mouse.