CATSPER1 Antibodies

AND CATSPER1 ELISA kits, CATSPER1 Proteins

Many biological assays use antibodies to detect CATSPER1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CATSPER1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CATSPER1 antibodies...

We validate the specificity of these antibodies to CATSPER1 by testing them on tissues known to express CATSPER1 positively and negatively. Browse below to find the CATSPER1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CATSPER1 Infographic by Boster Bio

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Anti-CATSPER1 Antibody

Western blot (WB) analysis of CATSPER1 polyclonal antibody at 1:1000 dilution
Lane1:A549 whole cell lysate
Lane2:Hela whole cell lysate
Lane3:SP2/0 whole cell lysate

Immunoprecipitation of HepG2 cell lysates using CATSPER1 pAb (Sepharose Bead Conjugate)#BD0048 (lane 2 and lane 3) and Nonspecific IgG Control (Sepharose Bead Conjugate)#BD0048 (lane 4)

Human, Mouse, Rat

$405
Cat # A04156
100ul

CATSPER1 Overview

Facts about Cation channel sperm-associated protein 1.

CATSPER1 3D structure. Source: alphafold

Cation channel sperm-associated protein 1 (CATSPER1)

Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses necessary for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. .

Gene Information

Human
Gene Name:	CATSPER1
Uniprot:	Q8NEC5
Entrez:	117144

Family

Belongs to:

cation channel sperm-associated (TC 1.A.1.19) family

Alternative Names

Cation channel sperm-associated protein 1

Molecular Weight

Mass (kDA):
90.091 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (66016752..66026518, complement)

Tissue Specificity

Testis-specific.

Subcellular Localizations

Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Specifically located in the principal piece of sperm tail.

Diseases

Spermatogenic failure 7 (SPGF7)

Interacting Proteins

AGR2
APOA2
CACNA1I
CHIC2
CHRD

EMD
KHDRBS2
KPRP
KRTAP10-11
KRTAP10-8

KRTAP10-9
KRTAP12-3
KRTAP4-11
KRTAP4-12
KRTAP4-7

KRTAP5-3
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3

KRTAP9-4
MDFI
MTUS2
NOTCH2NL
PLSCR1

PLSCR3
RFX6
RGS20
RIMBP3
SCRG1

SPRY2
TRAF2
TRIP6

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CATSPER1

References

PMID: 11595941 by Ren D., et al. A sperm ion channel required for sperm motility and male fertility.

PMID: 14688170 by Nikpoor P., et al. CatSper gene expression in postnatal development of mouse testis and in subfertile men with deficient sperm motility.