CCDC62 Antibodies

AND CCDC62 ELISA kits, CCDC62 Proteins

Many biological assays use antibodies to detect CCDC62, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCDC62 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCDC62 antibodies...

We validate the specificity of these antibodies to CCDC62 by testing them on tissues known to express CCDC62 positively and negatively. Browse below to find the CCDC62 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCDC62 Infographic by Boster Bio

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CCDC62 (NM_032573) Human Over-expression Lysate

Human

$960
Cat # LS084660
20 µg, 100 µg

CCDC62 Overview

Facts about Coiled-coil domain-containing protein 62.

CCDC62 3D structure. Source: alphafold

Coiled-coil domain-containing protein 62 (CCDC62)

Nuclear receptor coactivator that may enhance preferentially nitric oxide ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR.

Gene Information

Human
Gene Name:	CCDC62
Uniprot:	Q6P9F0
Entrez:	84660

Family

Belongs to:

No superfamily

Alternative Names

coiled-coil domain containing 62; FLJ40344; testis-specific protein TSP-NY; TSP-NY

Molecular Weight

Mass (kDA):
77.748 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (122773621..122827528)

Tissue Specificity

Highly expressed in adult testis. Expressed in both prostate epithelial and stromal cells, with predominant expression in epithelial cells (at protein level) (PubMed:19126643). Not detected in prostate by RT-PCR (PubMed:19165854). Overexpressed in various cancers.

Subcellular Localizations

Cytoplasm. Nucleus. Mainly nuclear.

Diseases

Parkinson Disease
Malignant Neoplasms
Malignant Neoplasm Of Prostate
Adenocarcinoma
Stomach Neoplasms
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Liver
Malignant Paraganglionic Neoplasm
Essential Tremor
Gastric Adenocarcinoma

Malignant Neoplasm Of Stomach
Prostatic Neoplasms
Serum Sickness
Inflammation
Movement Disorders

Pathways

Translation
Mrna Transcription
Aging
Immune Response
Neurogenesis
Cell Growth
Pathogenesis

Humoral Immune Response

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCDC62

References

PMID: 18563714 by Chen M., et al. ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells.

PMID: 19126643 by Chen M., et al. CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells.