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Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are important integrators of various mitogenenic and antimitogenic signals.
|Sequence:||6; NC_000006.12 (41934933..42048894, complement)|
Nucleus. Cytoplasm. Membrane. Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated to the nucleus through interaction with KIP/CIP family members.