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Cyclin-O Antibodies

AND CCNO ELISA kits, Cyclin-O Proteins

Many biological assays use antibodies to detect Cyclin-O, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cyclin-O in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cyclin-O antibodies...

We validate the specificity of these antibodies to Cyclin-O by testing them on tissues known to express CCNO positively and negatively. Browse below to find the CCNO antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCNO Infographic by Boster Bio

CCNO protein infographic

All CCNO Products

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Anti-Cyclin O CCNO Antibody

Western blot analysis of Cyclin O in mouse bladder tissue lysate with Cyclin O antibody at (A) 1 and (B) 2 μg/mL

Western blot analysis of Cyclin O in mouse bladder tissue lysate with Cyclin O antibody at (A) 1 and (B) 2 μg/mL

Human, Mouse, Rat

ELISA, WB

$481
Cat # A05899
0.1 mg

CCNO (NM_021147) Human Over-expression Lysate

CCNO Human Over-expression Lysates NM_021147

CCNO Human Over-expression Lysates NM_021147

Human

$628
Cat # LS010309
20 µg, 100 µg

CCNO Overview

Facts about Cyclin-O.

CCNO 3D structure

CCNO 3D structure. Source: alphafold

Cyclin-O (CCNO)

Specifically necessary for creation of multiciliated cells, possibly by encouraging a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.

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Gene Information

Human
Gene Name:	CCNO
Uniprot:	P22674
Entrez:	10309

Gene Information

Family

Belongs to:

cyclin family

Family

Alternative Names

CCNO cyclin O; CCNU; UDG2

Molecular Weight

Mass (kDA):
38.096 kDA

Molecular Weight

Genomic Context


Human

Location:	5q11.2
Sequence:	5; NC_000005.10 (55231152..55233717, complement)

Tissue Specificity

Present in respiratory cells (at protein level).

Subcellular Localizations

Cytoplasm. Localizes to the apical part of cytoplasm.

Subcellular Localization

Diseases

Hiv Infections
Immunologic Deficiency Syndromes
Hyperimmunoglobulin M Syndrome
Neoplasms
Lymphoma
Multiple Transition Abnormalities
B-cell Lymphomas
Malignant Neoplasms
Infective Disorder
Hyper-igm Immunodeficiency Syndrome, Type 1
Hepatitis

Hepatitis B
Patient Dependence On
Primary Effusion Lymphoma
Hypergammaglobulinemia
Innate Immune Response
Retroviridae Infections

Disease

Pathways

Dna Repair
Cell Cycle
Dna Replication
Cell Proliferation
Reverse Transcription
Dna Deamination
Localization
Cell Cycle Phase
G1 Phase
Mitosis
Cellular Process
Immune Response
Oxidative Demethylation

Chromosome Segregation
Cell Cycle Arrest
Demethylation
Error-prone Translesion Synthesis
Translesion Synthesis
Cell Death
S Phase

Pathways

PTMs

Deamination
Cleavage
Phosphorylation

Demethylation
Deglycosylation
Ubiquitination

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCNO

References

PMID: 2001396 by Muller S.J., et al. Isolation and characterization of a human cDNA encoding uracil-DNA glycosylase.

PMID: 8419333 by Muller S.J., et al. Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase.