CMRF35-like molecule 8 (CD300A)

Inhibitory receptor which might lead to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:10746781, PubMed:16339535, PubMed:9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 although not TRIF through activation of PTPN6 (PubMed:22043923).

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