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Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal centre B cells (PubMed:10727470). Functions as costimulator to promote B cell responses to antigenic stimulation; promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631).
|Sequence:||19; NC_000019.10 (8302127..8308358, complement)|
Detected in the germinal center (GC) of lymphoid follicles (at protein level) (PubMed:11418631). Expressed abundantly on follicular dendritic cells (FDCs) (PubMed:10727470).
Cell membrane; Single-pass type I membrane protein.