CD53 Antibodies

AND CD53 ELISA kits, CD53 Proteins

Many biological assays use antibodies to detect CD53, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD53 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD53 antibodies...

We validate the specificity of these antibodies to CD53 by testing them on tissues known to express CD53 positively and negatively. Browse below to find the CD53 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for CD53? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CD53 Western Blot Guide

CD53 Infographic by Boster Bio

All CD53 Products

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Product

Figures

Specificity

Applications

Price

Anti-CD53 Monoclonal Antibody

Western blot analysis of CD53 expression in Jurkat cell lysate

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M06249
100 μl

CD53 (NM_000560) Human Over-expression Lysate

Human

$628
Cat # LS000963
20 µg, 100 µg

CD53 (NM_000560) Human Recombinant Protein

Coomassie blue staining of purified CD53 protein

$1249
Cat # PROTP19397
20 µg

CD53 Overview

Facts about Leukocyte surface antigen CD53.

CD53 3D structure. Source: alphafold

Leukocyte surface antigen CD53 (CD53)

Required for efficient formation of myofibers in regenerating muscle in the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).

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Gene Information

Human
Gene Name:	CD53
Uniprot:	P19397
Entrez:	963

Family

Belongs to:

tetraspanin (TM4SF) family

Alternative Names

antigen MOX44 identified by monoclonal MRC-OX44; CD53 antigentetraspanin-25; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; CD53; cell surface antigen; Cell surface glycoprotein CD53; MOX44; MOX44transmembrane glycoprotein; Tetraspanin-25; TSPAN25; tspan-25; TSPAN25leukocyte surface antigen CD53

Molecular Weight

Mass (kDA):
24.341 kDA

Genomic Context


Human

Location:	1p13.3
Sequence:	1; NC_000001.11 (110871167..110899936)

Tissue Specificity

B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.

Subcellular Localizations

Cell membrane. Cell junction. Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.

Diseases

Tissue Adhesions
Neoplasms
Lymphoma
Neoplasm Metastasis
Inflammation
Leukemia
B-cell Lymphomas
Melanoma
Malignant Neoplasms
Hiv Infections
Immunologic Deficiency Syndromes
Rheumatoid Arthritis
Malignant Paraganglionic Neoplasm

Arthritis
Inflammatory Response
Infective Disorder
Intestinal Schistosomiasis
Sarcoma
Carcinoma
T-cell Lymphoma

Interacting Proteins

EMP1

Pathways

Cell Activation
Cell Adhesion
Localization
Cell Proliferation
Glycosylation
Transport
B Cell Activation
Leukocyte Differentiation
Pathogenesis
Aging
Inflammatory Response
Cell Cycle
Cell Motility

Immune Response
Cell Death
Rna Interference
T Cell Activation
Leukocyte Activation
Cell Division
Cell Differentiation

PTMs

Phosphorylation
Glycosylation
Cleavage

Reduction
Dephosphorylation
Palmitoylation

Ribosylation

Research Areas

Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD53

References

PMID: 1700763 by Angelisova P., et al. The human leucocyte surface antigen CD53 is a protein structurally similar to the CD37 and MRC OX-44 antigens.

PMID: 2258620 by Amiot M.; Identification and analysis of cDNA clones encoding CD53. A pan- leukocyte antigen related to membrane transport proteins.