CD59B glycoprotein Antibodies

AND Cd59b ELISA kits, CD59B glycoprotein Proteins

Many biological assays use antibodies to detect CD59B glycoprotein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD59B glycoprotein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD59B glycoprotein antibodies...

We validate the specificity of these antibodies to CD59B glycoprotein by testing them on tissues known to express Cd59b positively and negatively. Browse below to find the Cd59b antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cd59b Infographic by Boster Bio

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Cd59b Overview

Facts about CD59B glycoprotein.

Cd59b 3D structure. Source: alphafold

CD59B glycoprotein (Cd59b)

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).

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Gene Information

Mouse
Gene Name:	Cd59b
Uniprot:	P58019
Entrez:	333883

Family

Belongs to:

No superfamily

Alternative Names

CD59b

Molecular Weight

Mass (kDA):
14.227 kDA

Genomic Context


Mouse

Location:	2\|2 E2
Sequence:	2;

Diseases

Paroxysmal Nocturnal Hemoglobinuria
Hemoglobinuria
Hemoglobinuria, Paroxysmal
Hemolysis (disorder)
Neoplasms
Anemia
Malignant Neoplasms
Inflammation
Aplastic Anemia
Tissue Adhesions
Leukemia
Thrombosis
Carcinoma

Anemia, Hemolytic
Lymphoma
Autoimmune Reaction
Malignant Paraganglionic Neoplasm
Dysmyelopoietic Syndromes
Pancytopenia
Hematological Disease

Pathways

Complement Activation
Pathogenesis
Cytolysis
Cell Activation
Immune Response
Localization
Cell Death
Secretion
Glycosylation
Cell Proliferation
T Cell Activation
Complement-dependent Cytotoxicity
Inflammatory Response

Endocytosis
Transport
Phagocytosis
Cell Adhesion
Cell Killing
Coagulation
Regeneration

PTMs

Glycosylation
Cleavage
Gpi Anchoring
Phosphorylation
Acylation
Biotinylation
Deamination
Ubiquitination

Acetylation
Dephosphorylation
Oxidation
Methylation
Geranylgeranylation
Ribosylation
Reduction
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cd59b

References

PMID: 10946279 by Qian Y.-M., et al. Identification and functional characterization of a new gene encoding the mouse terminal complement inhibitor CD59.

PMID: 11471050 by Qin X., et al. Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b.