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- Table of Contents
CDC25A Antibodies
AND CDC25A ELISA kits, CDC25A Proteins
Many biological assays use antibodies to detect CDC25A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC25A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC25A antibodies...
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CDC25A Infographic by Boster Bio
All CDC25A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1105
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1105
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2232
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2232
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2370
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2370
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2543
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2543
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
IHC, WB
$405
Cat # A01433-1
100ul
Cat # A01433-1
100ul
CDC25A Overview
Facts about M-phase inducer phosphatase 1.
M-phase inducer phosphatase 1 (CDC25A)
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity.
Also dephosphorylates CDK2 in complex with cyclin E, in vitro. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC25A |
| Uniprot: | P30304 |
| Entrez: | 993 |
Family
| Belongs to: |
|---|
| MPI phosphatase family |
Alternative Names
CDC25A; CDC25A2; CDC25A2-CAG isoform; cell division cycle 25 homolog A (S. cerevisiae); cell division cycle 25 homolog A (S. pombe); cell division cycle 25A; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1
Molecular Weight
Mass (kDA):
59.087 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (48157146..48188417, complement) |
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Cell Transformation, Neoplastic
- Retinoblastoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Leukemia
- Liver Carcinoma
- Malignant Neoplasm Of Lung
- Genomic Instability
- Genotoxic Stress
Interacting Proteins
- RAF1
- YWHAB
- YWHAQ
- YWHAZ
Pathways
- Cell Cycle
- Cell Cycle Arrest
- Cell Proliferation
- S Phase
- Cell Growth
- Mitosis
- Cell Division
- Dna Replication
- Cell Death
- Dna Damage Checkpoint
- G1 Phase
- Dna Repair
- Cell Cycle Checkpoint
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Acetylation
- Ubiquitination
- Methylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC25A
bosterbio.com/bosterbio-gene-info-cards/CDC25A
References
PMID: 1836978 by Galaktionov K.I., et al. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins.
PMID: 11139144 by Wegener S., et al. Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.