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- Table of Contents
Designing a Western blot for CDC6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDC6 Western Blot GuideFacts about Cell division control protein 6 homolog.
Involved in the initiation of DNA replication.
Also participates in checkpoint controls that guarantee DNA replication is completed until mitosis is initiated..
| Human | |
|---|---|
| Gene Name: | CDC6 |
| Uniprot: | Q99741 |
| Entrez: | 990 |

| Belongs to: |
|---|
| CDC6/cdc18 family |

CDC18LHsCDC18; Cdc18-related protein; CDC6 (cell division cycle 6, S. cerevisiae) homolog; CDC6 cell division cycle 6 homolog (S. cerevisiae); CDC6 cell division cycle 6 homolog; CDC6-related protein; cell division control protein 6 homolog; cell division cycle 6 homolog (S. cerevisiae); cell division cycle 6 protein; HsCdc18; HsCDC6; p62(cdc6)
Mass (kDA):
62.72 kDA

| Human | |
|---|---|
| Location: | 17q21.2 |
| Sequence: | 17; NC_000017.11 (40287878..40304657) |
Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895).






PMID: 8990175 by Williams R.S., et al. A human protein related to yeast Cdc6p.
PMID: 9566895 by Saha P., et al. Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.