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- Table of Contents
CDC6 Antibodies
AND CDC6 ELISA kits, CDC6 Proteins
Many biological assays use antibodies to detect CDC6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC6 antibodies...
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CDC6 Infographic by Boster Bio
All CDC6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1106
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1106
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2021
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2021
1 kit, containing two 96-well plates and all necessary reagents
CDC6 Overview
Facts about Cell division control protein 6 homolog.
Cell division control protein 6 homolog (CDC6)
Involved in the initiation of DNA replication.
Also participates in checkpoint controls that guarantee DNA replication is completed until mitosis is initiated..
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC6 |
| Uniprot: | Q99741 |
| Entrez: | 990 |
Family
| Belongs to: |
|---|
| CDC6/cdc18 family |
Alternative Names
CDC18LHsCDC18; Cdc18-related protein; CDC6 (cell division cycle 6, S. cerevisiae) homolog; CDC6 cell division cycle 6 homolog (S. cerevisiae); CDC6 cell division cycle 6 homolog; CDC6-related protein; cell division control protein 6 homolog; cell division cycle 6 homolog (S. cerevisiae); cell division cycle 6 protein; HsCdc18; HsCDC6; p62(cdc6)
Molecular Weight
Mass (kDA):
62.72 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.2 |
| Sequence: | 17; NC_000017.11 (40287878..40304657) |
Subcellular Localizations
Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895).
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Retinoblastoma
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Carcinogenesis
- Hyperplasia
- Neoplasm Metastasis
- Malignant Neoplasm Of Prostate
- Genomic Instability
- Uterine Cervical Neoplasm
Interacting Proteins
- CDK1
- CDKN1A
- CDT1
- MCM7
- PLK1
Pathways
- Dna Replication
- Cell Cycle
- S Phase
- Mitosis
- Cell Division
- G1 Phase
- Cell Proliferation
- Dna Replication Initiation
- Localization
- Proteolysis
- Anaphase
- Regulation Of Dna Replication
- M Phase
PTMs
- Phosphorylation
- Ubiquitination
- Cleavage
- Dephosphorylation
- Acetylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC6
bosterbio.com/bosterbio-gene-info-cards/CDC6
References
PMID: 8990175 by Williams R.S., et al. A human protein related to yeast Cdc6p.
PMID: 9566895 by Saha P., et al. Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.