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- Table of Contents
CDC7 Antibodies
AND CDC7 ELISA kits, CDC7 Proteins
Many biological assays use antibodies to detect CDC7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC7 antibodies...
Designing a Western blot for CDC7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDC7 Western Blot GuideCDC7 Infographic by Boster Bio
All CDC7 Products
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CDC7 Overview
Facts about Cell division cycle 7-related protein kinase.
Cell division cycle 7-related protein kinase (CDC7)
Appears to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC7 |
| Uniprot: | O00311 |
| Entrez: | 8317 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; CDC7 cell division cycle 7 (S. cerevisiae); CDC7L1MGC117361; CDC7-related kinase; cell division cycle 7 (S. cerevisiae); cell division cycle 7 homolog (S. cerevisiae); cell division cycle 7-like protein 1; cell division cycle 7-related protein kinase; EC 2.7.11.1; HsCDC7; Hsk1; huCdc7; MGC126237; MGC126238
Molecular Weight
Mass (kDA):
63.888 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p22.1 |
| Sequence: | 1; NC_000001.11 (91498968..91525764) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Genomic Instability
- Stenosis
- Ataxia
- Carcinoma
- Glaucoma
- Melanoma
- Lymphoma
- Chromosomal Duplication
- Ataxia Telangiectasia
- Malignant Neoplasm Of Breast
Interacting Proteins
- DBF4
- MCMBP
- ZBTB8B
Pathways
- Dna Replication
- Cell Cycle
- S Phase
- Cell Division
- Mitosis
- Cytokinesis
- Localization
- Meiosis
- Anaphase
- G1 Phase
- Cell Death
- Dna Repair
- Chromosome Segregation
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- DNA Repair
- DNA replication, Transcription, Translation and Splicing
- GPCR
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC7
bosterbio.com/bosterbio-gene-info-cards/CDC7
References
PMID: 9250678 by Sato N., et al. Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7.
PMID: 9573348 by Hess G.F., et al. A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines.