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- Table of Contents
Cadherin-1 Antibodies
AND CDH1 ELISA kits, Cadherin-1 Proteins
Many biological assays use antibodies to detect Cadherin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cadherin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cadherin-1 antibodies...
Designing a Western blot for Cadherin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDH1 Western Blot GuideCDH1 Infographic by Boster Bio
All CDH1 Products
Product
Figures
Specificity
Applications
Price
Anti-E Cadherin 1/CDH1 Antibody Picoband®
71 Citations
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # PB9561
100 μg/vial
Cat # PB9561
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00063-2
100 μg/vial
Cat # M00063-2
100 μg/vial
Human
ELISA
$499
Cat # EK0561
96 wells/kit, with removable strips.
Cat # EK0561
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0562
96 wells/kit, with removable strips.
Cat # EK0562
96 wells/kit, with removable strips.
Anti-E-cadherin/Cdh1 Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A00063-3
100 µg/vial
Cat # A00063-3
100 µg/vial
Anti-OB Cadherin/CDH11 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04419-1
100 μg/vial
Cat # A04419-1
100 μg/vial
Anti-E Cadherin Rabbit Monoclonal Antibody
5 Citations
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00063-4
100 μl
Cat # M00063-4
100 μl
Zebrafish
IHC, WB
$470
Cat # AZQ90Z37
100 μg/vial
Cat # AZQ90Z37
100 μg/vial
Human
ELISA
$750
Cat # EK2099
96 wells/kit, with removable strips.
Cat # EK2099
96 wells/kit, with removable strips.
Mouse
ELISA
$500
Cat # EZ0562
5 plates/kit
Cat # EZ0562
5 plates/kit
Rat
ELISA
$499
Cat # EK1434
96 wells/kit, with removable strips.
Cat # EK1434
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A10888-1
100 μg/vial
Cat # A10888-1
100 μg/vial
Mouse
ELISA
$499
Cat # FEK0562
96 wells/kit, with removable strips.
Cat # FEK0562
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK2068
96 wells/kit, with removable strips.
Cat # EK2068
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK1998
96 wells/kit, with removable strips.
Cat # EK1998
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00063-1
100 μl
Cat # M00063-1
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC
$370
Cat # A06389-1
100 μg/vial
Cat # A06389-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00064
100 μl
Cat # M00064
100 μl
Human, Mouse, Rat
IHC, WB
$370
Cat # M01986-1
100 μl/vial
Cat # M01986-1
100 μl/vial
Human
IHC, WB
$449
Cat # M00063-3
100ul
Cat # M00063-3
100ul
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01986-1
100 μg/vial
Cat # A01986-1
100 μg/vial
Human, Mouse, Rat
IF, WB
$523
Cat # M01986
100 µl
Cat # M01986
100 µl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M06389-1
100 μg
Cat # M06389-1
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00063-6
100 μg
Cat # M00063-6
100 μg
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A00063-1
100ul
Cat # A00063-1
100ul
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M06389-2
100 μg
Cat # M06389-2
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M04419
100 μg
Cat # M04419
100 μg
Human
$628
Cat # LS001008
20 µg, 100 µg
Cat # LS001008
20 µg, 100 µg
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A03219-2
100 μl/vial
Cat # A03219-2
100 μl/vial
CDH1 Overview
Facts about Cadherin-1.
Cadherin-1 (CDH1)
Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a powerful invasive suppressor role.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDH1 |
| Uniprot: | P12830 |
| Entrez: | 999 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Arc-1; CAD1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); Cadherin-1; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324 antigen; CD324; CDH1; CDHE; cell-CAM 120/80; Cell-CAM120/80; ECAD; ECadherin; E-Cadherin; Epithelial cadherin; LCAM; L-CAM; UVOE-Cadherin; Uvomorulin
Molecular Weight
Mass (kDA):
97.456 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (68737292..68835537) |
Tissue Specificity
Non-neural epithelial tissues.
Subcellular Localizations
Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Stomach
- Stomach Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Tissue Adhesions
- Neoplasm Metastasis
- Carcinogenesis
- Cell Invasion
- Adenocarcinoma
Interacting Proteins
- Cbll1
- CDC27
- CTNNA1
- CTNNB1
- ECT2
- EGFR
- FGFR1
- LIMA1
- PPP1CA
- PRKD1
Pathways
- Methylation
- Cell Cycle
- Mitosis
- Dna Methylation
- Anaphase
- Proteolysis
- Cell Adhesion
- Pathogenesis
- Localization
- S Phase
- Cell Proliferation
- Cell Division
- Cell-cell Adhesion
PTMs
- Methylation
- Phosphorylation
- Ubiquitination
- Demethylation
- Dephosphorylation
- Cleavage
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDH1
bosterbio.com/bosterbio-gene-info-cards/CDH1
References
PMID: 8459805 by Bussemakers M.J.G., et al. Molecular cloning and characterization of the human E-cadherin cDNA.
PMID: 8127895 by Oda T., et al. E-cadherin gene mutations in human gastric carcinoma cell lines.
73 Publications of Boster Cadherin-1 Antibodies & ELISA Kits
- PubMed ID: PMID:30210698, Identification and differentiation therapy strategy of pterygium in vitro
- PubMed ID: PMID:26722422, Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in C...
- PubMed ID: PMID:26617787, RAC1 overexpression promotes the proliferation, migration and epithelial-mesench...
- PubMed ID: PMID:26617724, Expression of RKIP, E-cadherin and NF-kB p65 in esophageal squamous cell carcino...
- PubMed ID: 10.7150/jca.49138, LINC00184 involved in the regulatory network of ANGPT2 via ceRNA mediated miR-14...
- PubMed ID: 10.4149/neo_2016_603, Silencing of ATPase family AAA domain-containing protein 2 inhibits migration an...
- PubMed ID: 10.3892/ijo.2016.3343, Overexpression of SDF-1 activates the NF-κB pathway to induce epithelial to mes...
- PubMed ID: 10.3892/ijmm.2021.5071, Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasio...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2011.23.036, Effect of anaphylatoxin C3a, C5a on the tubular epithelial-myofibroblast transdi...
- PubMed ID: 10.3748/wjg.v18.i47.7070, Connective tissue growth factor is overexpressed in human hepatocellular carcino...
- PubMed ID: 10.2147/OTT.S93738, Overexpression of Livin promotes migration and invasion of colorectal cancer cel...
- PubMed ID: 10.1186/s12935-020-1150-1, Hsa_circ_0137008 suppresses the malignant phenotype in colorectal cancer by acti...
- PubMed ID: 10.1177/0885328216688337, Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials...
- PubMed ID: 10.1111/bcpt.12616, Placental Growth Factor Triggers Epithelial‐to‐Mesenchymal Transition‐like...
- PubMed ID: 10.1038/labinvest.2013.108, All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregula...
- PubMed ID: 10.1038/bjc.2015.444, Regulator of cullins-1 expression knockdown suppresses the malignant progression...
- PubMed ID: 10.1016/j.placenta.2021.06.004, Iodothyronine deiodinase 2 (DiO2) regulates trophoblast cell line cycle, invasio...
- PubMed ID: 10.1016/j.jsps.2021.12.009, Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal canc...
- PubMed ID: 10.1016/j.jff.2021.104661, Genetically encoded probiotic EcN 1917 alleviates alcohol-induced acute liver in...
- PubMed ID: 10.1016/j.carbpol.2017.06.072, Preparation and pharmacological evaluation of norcantharidin-conjugated carboxym...
- PubMed ID: 10.1016/j.apjtm.2016.04.022, Experiment research of cisplatin implants inhibiting transplantation tumor growt...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page