Cyclin-dependent kinase 10 (CDK10)

Cyclin-dependent kinase which phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators like PKN2.

Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and marketing of RhoA signaling (PubMed:27104747). .