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- Table of Contents
CDK10 Antibodies
AND CDK10 ELISA kits, CDK10 Proteins
Many biological assays use antibodies to detect CDK10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDK10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDK10 antibodies...
Designing an IHC experiment for CDK10? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CDK10 IHC GuideCDK10 Infographic by Boster Bio
All CDK10 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1818
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1818
1 kit, containing one 96-well plate and all necessary reagents
CDK10 Overview
Facts about Cyclin-dependent kinase 10.
Cyclin-dependent kinase 10 (CDK10)
Cyclin-dependent kinase which phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators like PKN2.
Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and marketing of RhoA signaling (PubMed:27104747). .
Gene Information
| Human | |
|---|---|
| Gene Name: | CDK10 |
| Uniprot: | Q15131 |
| Entrez: | 8558 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
Cell division protein kinase 10; cyclin-dependent kinase (CDC2-like) 10; cyclin-dependent kinase 10; cyclin-dependent kinase related protein; EC 2.7.11; EC 2.7.11.22; PISSLRECDC2-related protein kinase; serine/threonine protein kinase PISSLRE; Serine/threonine-protein kinase PISSLRE
Molecular Weight
Mass (kDA):
41.038 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q24.3 |
| Sequence: | 16; NC_000016.10 (89686612..89696354) |
Subcellular Localizations
Cytoplasm, cytoskeleton, cilium basal body.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Carcinoma
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Stenosis
- Biliary Tract Cancer
- Seminoma
- Liver Damage
Interacting Proteins
- CCNQ
- ETS2
- HSP90AB1
- PIN1
Pathways
- Cell Cycle
- Cell Proliferation
- Methylation
- Cell Division
- Dna Methylation
- Cell Growth
- Transport
- Cell Activation
- Cell Migration
- M Phase
- Hepatocyte Proliferation
- Cell Cycle Arrest
- Reverse Transcription
PTMs
- Phosphorylation
- Methylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDK10
bosterbio.com/bosterbio-gene-info-cards/CDK10
References
PMID: 8208557 by Grana X., et al. PISSLRE, a human novel CDC2-related protein kinase.
PMID: 8084611 by Brambilla R., et al. Molecular cloning of PISSLRE, a novel putative member of the cdk family of protein serine/threonine kinases.