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- Table of Contents
Cyclin-dependent kinase 9 Antibodies
AND CDK9 ELISA kits, Cyclin-dependent kinase 9 Proteins
Many biological assays use antibodies to detect Cyclin-dependent kinase 9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cyclin-dependent kinase 9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cyclin-dependent kinase 9 antibodies...
Designing a Western blot for Cyclin-dependent kinase 9? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDK9 Western Blot GuideDesigning an IHC experiment for Cyclin-dependent kinase 9? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CDK9 IHC GuideCDK9 Infographic by Boster Bio
All CDK9 Products
Product
Figures
Specificity
Applications
Price
Anti-Claudin 7/CLDN-7 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03851-3
100 μg/vial
Cat # A03851-3
100 μg/vial
Anti-Nr0b2 Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03866-1
100 μg/vial
Cat # A03866-1
100 μg/vial
Anti-AFF4 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$370
Cat # A03824
100 μg/vial
Cat # A03824
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03870-2
100 μg/vial
Cat # A03870-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03831-3
100 μg/vial
Cat # A03831-3
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03863-3
100 µg/vial
Cat # A03863-3
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A03826-1
100 μg/vial
Cat # A03826-1
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03862-2
100 μg/vial
Cat # A03862-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03842-1
100 μg/vial
Cat # A03842-1
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03840-1
100 μg/vial
Cat # A03840-1
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M00794
100 μl
Cat # M00794
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03834-1
100 µg/vial
Cat # A03834-1
100 µg/vial
Human
ELISA, Flow Cytometry, WB
$370
Cat # A03832-2
100 μg/vial
Cat # A03832-2
100 μg/vial
CDK9 Overview
Facts about Cyclin-dependent kinase 9.
Cyclin-dependent kinase 9 (CDK9)
Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase set (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which eases the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP.
Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDK9 |
| Uniprot: | P50750 |
| Entrez: | 1025 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
C-2k; CDC2L4CTK1; CDC2-related kinase; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); cyclin-dependent kinase 9; EC 2.7.11; EC 2.7.11.22; EC 2.7.11.23; PITALRE; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK
Molecular Weight
Mass (kDA):
42.778 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.11 |
| Sequence: | 9; NC_000009.12 (127786034..127790792) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Nucleus. Cytoplasm. Nucleus, PML body. Accumulates on chromatin in response to replication stress. Complexed with CCNT1 in nuclear speckles, but uncomplexed form in the cytoplasm. The translocation from nucleus to cytoplasm is XPO1/CRM1-dependent. Associates with PML body when acetylated.
Diseases
- Hiv Infections
- Immunologic Deficiency Syndromes
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Hypertrophy
- Retinoblastoma
- Cardiac Hypertrophy
- Cell Transformation, Neoplastic
- Acquired Immunodeficiency Syndrome
- Carcinoma
Interacting Proteins
- ATR
- ATRIP
- CCNT1
- CDC37
- CLSPN
- FKBP5
- HEXIM1
- HSP90AA1
- HSP90AB1
- JMJD6
Pathways
- Cell Cycle
- Localization
- Viral Replication
- Cell Death
- Cell Growth
- Viral Transcription
- Rna Interference
- Cell Division
- Hyperphosphorylation
- Chromatin Remodeling
- Cell Differentiation
- Translation
- Cell Proliferation
PTMs
- Phosphorylation
- Acetylation
- Dephosphorylation
- Methylation
Research Areas
- Cancer
- Cell Cycle and Replication
- Signal Transduction
- Virology, Bacteria and Parasites
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDK9
bosterbio.com/bosterbio-gene-info-cards/CDK9
References
PMID: 8170997 by Grana X., et al. PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro.
PMID: 7695608 by Best J.L., et al. Cloning of a full-length cDNA sequence encoding a cdc2-related protein kinase from human endothelial cells.
1 Publications of Boster Cyclin-dependent kinase 9 Antibodies & ELISA Kits
- PubMed ID: 10.1097/CEJ.0b013e3283431c08, Profile of protein expression of the colon cancer cell line SW480 with survivin/...
*More publications can be found for each product on its corresponding product page