- Table of Content
Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g.
|protein kinase superfamily|
|Sequence:||9; NC_000009.12 (127786034..127790792)|
Nucleus. Cytoplasm. Nucleus, PML body. Accumulates on chromatin in response to replication stress. Complexed with CCNT1 in nuclear speckles, but uncomplexed form in the cytoplasm. The translocation from nucleus to cytoplasm is XPO1/CRM1-dependent. Associates with PML body when acetylated.