Homeobox protein CDX-1 Antibodies

AND CDX1 ELISA kits, Homeobox protein CDX-1 Proteins

Many biological assays use antibodies to detect Homeobox protein CDX-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein CDX-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein CDX-1 antibodies...

We validate the specificity of these antibodies to Homeobox protein CDX-1 by testing them on tissues known to express CDX1 positively and negatively. Browse below to find the CDX1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Homeobox protein CDX-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CDX1 Western Blot Guide

CDX1 Infographic by Boster Bio

All CDX1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cdx1 Rabbit Monoclonal Antibody

Western blot analysis of Cdx1 expression in Caco-2 cell lysate

Human

IF, ICC, WB

$370
Cat # M04522-1
100 μl/vial

CDX1 (NM_001804) Human Over-expression Lysate

Human

$628
Cat # LS001044
20 µg, 100 µg

CDX1 Overview

Facts about Homeobox protein CDX-1.

CDX1 3D structure. Source: alphafold

Homeobox protein CDX-1 (CDX1)

Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306).

Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the gut.

Gene Information

Human
Gene Name:	CDX1
Uniprot:	P47902
Entrez:	1044

Family

Belongs to:

Caudal homeobox family

Alternative Names

caudal type homeo box transcription factor 1; caudal type homeobox 1; caudal type homeobox transcription factor 1; Caudal-type homeobox protein 1; caudal-type homeobox protein CDX1; homeobox protein CDX-1; MGC116915

Molecular Weight

Mass (kDA):
28.138 kDA

Genomic Context


Human

Location:	5q32
Sequence:	5; NC_000005.10 (150166778..150184558)

Tissue Specificity

Intestinal epithelium.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Metaplasia
Carcinoma
Adenocarcinoma
Colorectal Neoplasms
Colonic Neoplasms
Colorectal Cancer
Malignant Tumor Of Colon
Stomach Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasm Of Stomach

Carcinogenesis
Precancerous Conditions
Barrett Esophagus
Gastroesophageal Reflux Disease
Adenoma
Inflammation
Gastritis

Interacting Proteins

CEBPA

Pathways

Cell Proliferation
Pathogenesis
Methylation
Cell Differentiation
Gastrulation
Localization
Dna Methylation
Cell Growth
Cell-cell Adhesion
Epithelial Cell Proliferation
Cell Adhesion
Cell Cycle
Transdifferentiation

Demethylation
Cell Migration
Segmentation
Oncogenesis
Somitogenesis
Hypersensitivity
Endoderm Development

PTMs

Methylation
Phosphorylation

Demethylation
Reduction

Acetylation

Research Areas

Epigenetics

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDX1

References

PMID: 8530027 by Bonner C.A., et al. Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene.

PMID: 9036867 by Mallo G.V., et al. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis.