CEP162 Antibodies

AND CEP162 ELISA kits, CEP162 Proteins

Many biological assays use antibodies to detect CEP162, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP162 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP162 antibodies...

We validate the specificity of these antibodies to CEP162 by testing them on tissues known to express CEP162 positively and negatively. Browse below to find the CEP162 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP162 Infographic by Boster Bio

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CEP162 Overview

Facts about Centrosomal protein of 162 kDa.

CEP162 3D structure. Source: alphafold

Centrosomal protein of 162 kDa (CEP162)

Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule.

Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules.

Gene Information

Human
Gene Name:	CEP162
Uniprot:	Q5TB80
Entrez:	22832

Family

Belongs to:

CEP162 family

Alternative Names

Centrosomal protein of 162 kDa

Molecular Weight

Mass (kDA):
161.943 kDA

Genomic Context


Human

Location:	6q14.2-q14.3
Sequence:	6; NC_000006.12 (84124250..84227889, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Nucleus. Localizes to the distal end of centrioles throughout the cell cycle. During ciliogenesis, found at the cilia base. Localizes to spindle microtubules during mitosis.

Interacting Proteins

CEP120
CEP135
CEP290

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEP162

References

PMID: 11521196 by Munnia A., et al. Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor.

PMID: 16302001 by Leon A., et al. QN1/KIAA1009: a new essential protein for chromosome segregation and mitotic spindle assembly.