CEP295 Antibodies

AND CEP295 ELISA kits, CEP295 Proteins

Many biological assays use antibodies to detect CEP295, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP295 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP295 antibodies...

We validate the specificity of these antibodies to CEP295 by testing them on tissues known to express CEP295 positively and negatively. Browse below to find the CEP295 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP295 Infographic by Boster Bio

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CEP295 Overview

Facts about Centrosomal protein of 295 kDa.

CEP295 3D structure. Source: alphafold

Centrosomal protein of 295 kDa (CEP295)

Centriole-enriched protein which mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement. .

Gene Information

Human
Gene Name:	CEP295
Uniprot:	Q9C0D2
Entrez:	85459

Family

Belongs to:

No superfamily

Alternative Names

Centrosomal protein of 295 kDa

Molecular Weight

Mass (kDA):
295.176 kDA

Genomic Context


Human

Location:	11q21
Sequence:	11; NC_000011.10 (93661682..93730381)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton. Associates with both of the converted centrioles during G1 but becomes more enriched at the newly formed daughter (or unconverted) centrioles during S, G2, and early M phases (PubMed:25131205). In early S phase, localized at the procentriolar microtubule wall and enriched at the proximal ends of the centrioles in CENPJ- and CEP135-dependent manner (PubMed:27185865). Colocalizes with SASS6 an

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEP295

References

PMID: 20844083 by Knorz V.J., et al. Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731.

PMID: 25131205 by Izquierdo D., et al. Stabilization of cartwheel-less centrioles for duplication requires CEP295-mediated centriole-to-centrosome conversion.