CFHR1 Antibodies

AND CFHR1 ELISA kits, CFHR1 Proteins

Many biological assays use antibodies to detect CFHR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CFHR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CFHR1 antibodies...

We validate the specificity of these antibodies to CFHR1 by testing them on tissues known to express CFHR1 positively and negatively. Browse below to find the CFHR1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CFHR1 Infographic by Boster Bio

All CFHR1 Products

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Product

Figures

Specificity

Applications

Price

Anti-FHR1 CFHR1 Antibody

Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night

Human

ELISA, WB

$380
Cat # A03431
100ul

Human CFHR1 ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2165
96 wells/kit, with removable strips.

CFHL1 (CFHR1) (NM_002113) Human Over-expression Lysate

Human

$628
Cat # LS003078
20 µg, 100 µg

CFHR1 Overview

Facts about Complement factor H-related protein 1.

CFHR1 3D structure. Source: alphafold

Complement factor H-related protein 1 (CFHR1)

Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and economically compete with the physiological complement inhibitor CFH.

Can associate with lipoproteins and may play a role in lipid metabolism. .

Gene Information

Human
Gene Name:	CFHR1
Uniprot:	Q03591
Entrez:	3078

Family

Belongs to:

No superfamily

Alternative Names

BTA; CFHL1FHR-1; CFHLCFHR1P; CFHR1; complement factor H-related 1 pseudogene; Complement Factor Hrelated 1; Complement Factor H-related 1; complement factor H-related protein 1; FHR1; FHR1CFHL1P; H factor (complement)-like 1; H factor (complement)-like 2; H factor-like protein 1; H36-1; H36-2; H-factor-like 1; HFL1H36; HFL2; MGC104329

Molecular Weight

Mass (kDA):
37.651 kDA

Genomic Context


Human

Location:	1q31.3
Sequence:	1; NC_000001.11 (196819730..196832189)

Tissue Specificity

Expressed by the liver and secreted in plasma.

Subcellular Localizations

Secreted.

Diseases

Hemolytic-uremic Syndrome
Uremia Syndrome
Lyme Disease
Age Related Macular Degeneration
Hemolytic Uremic Syndrome, Atypical
Infective Disorder
Autoimmune Reaction
Kidney Diseases
Glomerulonephritis, Membranoproliferative
Inflammation
Glomerulonephritis
Autoimmune Diseases
Blind Vision

Kidney Failure
Malignant Neoplasms
Anemia
Kidney Failure, Chronic
Disease Of Capillaries
Neoplasms
Borrelia Infections

Pathways

Complement Activation
Pathogenesis
Secretion
Virulence
Phagocytosis
Immune Response
Gene Conversion
Proteolysis
Regulation Of Complement Activation
Opsonization
Cell Activation
Regulation Of Biological Process
Cell Migration

Aging
Brain Development
Adaptive Immune Response
Protein Secretion
Biosynthetic Process
Positive Regulation Of Cellular Process
Inflammatory Response

PTMs

Cleavage

Phosphorylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CFHR1

References

PMID: 1826708 by Estaller C., et al. Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.

PMID: 10781834 by Male D.A., et al. Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.