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- Table of Contents
Designing a Western blot for CHCHD10? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CHCHD10 Western Blot GuideFacts about Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial.
| Human | |
|---|---|
| Gene Name: | CHCHD10 |
| Uniprot: | Q8WYQ3 |
| Entrez: | 400916 |

| Belongs to: |
|---|
| No superfamily |

Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
Mass (kDA):
14.149 kDA

| Human | |
|---|---|
| Location: | 22q11.23 |
| Sequence: | 22; NC_000022.11 (23765834..23767972, complement) |
Ubiquitously expressed. Higher expression is observed in heart and liver.
Mitochondrion intermembrane space. Enriched at the cristae junctions.




PMID: 24934289 by Bannwarth S., et al. A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
PMID: 25428574 by Penttilae S., et al. Late onset spinal motor neuronopathy is caused by mutation in CHCHD10.