CHD1L Antibodies

AND CHD1L ELISA kits, CHD1L Proteins

Many biological assays use antibodies to detect CHD1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHD1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHD1L antibodies...

We validate the specificity of these antibodies to CHD1L by testing them on tissues known to express CHD1L positively and negatively. Browse below to find the CHD1L antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHD1L Infographic by Boster Bio

All CHD1L Products

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Anti-CHD1L Antibody

3 Q&As

Western Blot analysis of extracts from NIH-3T3, Jurkat, A549 cells, using CHD1L Polyclonal Antibody

Western blot analysis of lysates from HepG2 cells, using CHD1L antibody

Human, Mouse

ELISA, WB

$399
Cat # A05749
100μl

Anti-CHD1L Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CHD1L antibody

Human, Mouse

Flow Cytometry, IHC, WB

$405
Cat # A05749-1
100ul

CHD1L (NM_004284) Human Recombinant Protein

Coomassie blue staining of purified CHD1L protein

$1249
Cat # PROTQ86WJ1
20 µg

Anti-CHD1L Rabbit Monoclonal Antibody

1 Citations

Western blot analysis of CHD1L expression in A549 cell lysate

Human, Mouse

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M05749-1
100 μl/vial

CHD1L (NM_004284) Human Over-expression Lysate

Human

$960
Cat # LS009557
20 µg, 100 µg

CHD1L Overview

Facts about Chromodomain-helicase-DNA-binding protein 1-like.

CHD1L 3D structure. Source: alphafold

Chromodomain-helicase-DNA-binding protein 1-like (CHD1L)

DNA helicase that plays a part in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair.

Willing to catalyze nucleosome sliding in an ATP-dependent method. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.

Gene Information

Human
Gene Name:	CHD1L
Uniprot:	Q86WJ1
Entrez:	9557

Family

Belongs to:

SNF2/RAD54 helicase family

Alternative Names

ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHD1L; CHDL; chromodomain helicase DNA binding protein 1-like; chromodomain-helicase-DNA-binding protein 1-like; FLJ22530

Molecular Weight

Mass (kDA):
101 kDA

Genomic Context


Human

Location:	1q21.1
Sequence:	1; NC_000001.11 (147172747..147295766)

Tissue Specificity

Frequently overexpressed in hepatomacellular carcinomas.

Subcellular Localizations

Nucleus. Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1.

Diseases

Carcinoma
Neoplasms
Liver Carcinoma
Malignant Neoplasms
Liver Neoplasms
Neoplasm Metastasis
Cell Invasion
Hepatocarcinogenesis
Malignant Neoplasm Of Liver
Cell Transformation, Neoplastic
Congenital Abnormality

Mutation Abnormality
Stenosis
Subaortic Stenosis
Bone Neoplasms
Aneuploidy
Neoplasm Invasiveness

Interacting Proteins

PARP1

Pathways

Pathogenesis
Chromatin Remodeling
Cell Proliferation
Cell Migration
Mitosis
Dna Repair
Cellular Process
Immune Response
Rna Surveillance
Cell Motility

Regulation Of Dna Repair
Cell Growth
Chromatin Modification
Rna Interference
Kidney Development

PTMs

Methylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHD1L

References

PMID: 18023026 by Ma N.-F., et al. Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

PMID: 19661379 by Ahel D., et al. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.