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Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 in'Lys- 27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages.
|SNF2/RAD54 helicase family|
|Sequence:||1; NC_000001.11 (6101787..6180321, complement)|
Preferentially expressed in total brain, fetal brain, and cerebellum. It is also moderately expressed in the adrenal gland and detected in testis.
Nucleus. Associates with heterochromatin.