CHI3L2 Antibodies

AND CHI3L2 ELISA kits, CHI3L2 Proteins

Many biological assays use antibodies to detect CHI3L2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHI3L2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHI3L2 antibodies...

We validate the specificity of these antibodies to CHI3L2 by testing them on tissues known to express CHI3L2 positively and negatively. Browse below to find the CHI3L2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHI3L2 Infographic by Boster Bio

All CHI3L2 Products

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Product

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Specificity

Applications

Price

Human Chitinase 3-like 2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ15782
Starting from 10ug

CHI3L2 (NM_004000) Human Over-expression Lysate

CHI3L2 Human Over-expression Lysates NM_001025197

Human

$628
Cat # LS001117
20 µg, 100 µg

CHI3L2 Overview

Facts about Chitinase-3-like protein 2.

CHI3L2 3D structure. Source: alphafold

Chitinase-3-like protein 2 (CHI3L2)

Lectin that contrasts chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.

Gene Information

Human
Gene Name:	CHI3L2
Uniprot:	Q15782
Entrez:	1117

Family

Belongs to:

glycosyl hydrolase 18 family

Alternative Names

CHI3L2; Chitinase 3 like 2; Chitinase 3-like 2; chitinase-3-like protein 2; Chondrocyte protein 39; YKL39; YKL-39YKL39

Molecular Weight

Mass (kDA):
43.501 kDA

Genomic Context


Human

Location:	1p13.2
Sequence:	1; NC_000001.11 (111227080..111243440)

Tissue Specificity

Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta.

Subcellular Localizations

Secreted.

Diseases

Glioblastoma
Neoplasms
Glioblastoma Multiforme
Cerebral Amyloid Angiopathy
Amyloid Deposition
Glioma
Malignant Paraganglionic Neoplasm
Hypoxia
Crushing Injury
Brain Neoplasms
Degenerative Polyarthritis
Multiple Myeloma

Malignant Neoplasms
Low Grade Glioma
Innate Immune Response
Vascular Diseases
Senile Cerebral Amyloid Angiopathy
Senile Plaques
Alzheimer's Disease

Pathways

Cell Proliferation
Innate Immune Response
Proteolysis
Immune Response
Chondrocyte Differentiation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHI3L2

References

PMID: 8702629 by Hu B., et al. Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family.

PMID: 22742450 by Schimpl M., et al. Human YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding properties.