Choline kinase alpha Antibodies

AND CHKA ELISA kits, Choline kinase alpha Proteins

Many biological assays use antibodies to detect Choline kinase alpha, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Choline kinase alpha in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Choline kinase alpha antibodies...

We validate the specificity of these antibodies to Choline kinase alpha by testing them on tissues known to express CHKA positively and negatively. Browse below to find the CHKA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHKA Infographic by Boster Bio

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Choline kinase alpha (CHKA) (NM_001277) Human Over-expression Lysate

Choline kinase alpha (CHKA) Human Over-expression Lysates NM_001277

Human

$960
Cat # LS001119
20 µg, 100 µg

Anti-CHKA Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A04828-1
100 μl/vial

CHKA Overview

Facts about Choline kinase alpha.

CHKA 3D structure. Source: alphafold

Choline kinase alpha (CHKA)

Has a key role in phospholipid biosynthesis and might result in tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis.

Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine.

Gene Information

Human
Gene Name:	CHKA
Uniprot:	P35790
Entrez:	1119

Family

Belongs to:

choline/ethanolamine kinase family

Alternative Names

CHETK-alpha; CHK; choline kinase alpha; choline kinase; CK; CKIethanolamine kinase; EC 2.7.1.32; EC 2.7.1.82; EK; Ethanolamine kinase;

Molecular Weight

Mass (kDA):
52.249 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (68052859..68121389, complement)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Carcinoma
Mammary Neoplasms
Lung Neoplasms
Disease Of Adrenal Medulla
Non-small Cell Lung Carcinoma
Malignant Neoplasm Of Lung
Congenital Abnormality
Dystrophy
Prostatic Neoplasms

Deformity Of Bone
Cell Transformation, Neoplastic
Muscular Dystrophy
5,10-methylenetetrahydrofolate Reductase Deficiency
Adenocarcinoma
Cleft Palate
Malignant Paraganglionic Neoplasm

Pathways

Cell Proliferation
Regeneration
Excretion
Cdp-choline Pathway
Regulation Of Cell Proliferation
Secretion
Gene Silencing
Osteoblast Differentiation
Cytokine Production
Translation

Cell Cycle
Cell Growth
Bone Development
Rna Interference

PTMs

Phosphorylation

Reduction

Oxidation

Research Areas

Checkpoint signaling
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHKA

References

PMID: 1618328 by Hosaka K., et al. Cloning of a human choline kinase cDNA by complementation of the yeast cki mutation.

PMID: 19915674 by Gallego-Ortega D., et al. Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.