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N-chimaerin Antibodies
AND CHN1 ELISA kits, N-chimaerin Proteins
Many biological assays use antibodies to detect N-chimaerin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with N-chimaerin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop N-chimaerin antibodies...
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CHN1 Infographic by Boster Bio
All CHN1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M04240
100 µl
Cat # M04240
100 µl
Dog, Human, Monkey, Mouse, Rat
IHC, WB
$523
Cat # M04240-2
100 µl
Cat # M04240-2
100 µl
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M04240-1
100 µl
Cat # M04240-1
100 µl
CHN1 Overview
Facts about N-chimaerin.
N-chimaerin (CHN1)
GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CHN1 |
| Uniprot: | P15882 |
| Entrez: | 1123 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
a2-chimaerin; A-chimaerin; alpha-chimerin; ARHGAP2RhoGAP2; chimerin (chimaerin) 1; CHNDuane retraction syndrome 2; DURS2; NC; N-chimaerin; n-chimerin; Rho GTPase-activating protein 2; RHOGAP2
Molecular Weight
Mass (kDA):
53.172 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q31.1 |
| Sequence: | 2; NC_000002.12 (174798809..175005381, complement) |
Tissue Specificity
In neurons in brain regions that are involved in learning and memory processes.
Diseases
- Duane Retraction Syndrome
- Hepatitis
- Strabismus
- Esotropia
- Blepharoptosis
- Ocular Motility Disorders
- Nephropathy Toxic
- Prion Diseases
- Acquired Immunodeficiency Syndrome
- Malignant Neoplasm Of Breast
- Mirror Movements Disorder
- Malignant Neoplasms
- Chondrosarcoma
Interacting Proteins
- HEMK1
- NCK2
Pathways
- Innervation
- Transport
- Cell Adhesion
- Reverse Transcription
- Dna Amplification
- Locomotion
- Neurogenesis
PTMs
- Deacetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHN1
bosterbio.com/bosterbio-gene-info-cards/CHN1
References
PMID: 2299665 by Hall C., et al. Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene.
PMID: 1445199 by Lim H.H., et al. Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence.