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CHRM4 Antibodies

AND CHRM4 ELISA kits, CHRM4 Proteins

Many biological assays use antibodies to detect CHRM4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRM4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRM4 antibodies...

We validate the specificity of these antibodies to CHRM4 by testing them on tissues known to express CHRM4 positively and negatively. Browse below to find the CHRM4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRM4 Infographic by Boster Bio

CHRM4 protein infographic

All CHRM4 Products

Product

Figures

Specificity

Applications

Price

Anti-mAChR M4 (P277) Antibody

Human, Rat

WB

$405
Cat # A08161
100ul

Anti-mAChR M4 Antibody

Human, Mouse, Rat

ELISA, IF, WB

$380
Cat # A08161-1
100ul

Muscarinic Acetylcholine Receptor M4 (CHRM4) (NM_000741) Human Over-expression Lysate

Human

$960
Cat # LS001132
100 µg

CHRM4 Overview

Facts about Muscarinic acetylcholine receptor M4.

CHRM4 3D structure

CHRM4 3D structure. Source: alphafold

Muscarinic acetylcholine receptor M4 (CHRM4)

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.

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Gene Information

Human
Gene Name:	CHRM4
Uniprot:	P08173
Entrez:	1132

Gene Information

Family

Belongs to:

G-protein coupled receptor 1 family

Family

Alternative Names

cholinergic receptor, muscarinic 4; CHRM4; HM4; M4; M4R; mAChR M4; muscarinic acetylcholine receptor M4

Molecular Weight

Mass (kDA):
53.049 kDA

Molecular Weight

Genomic Context


Human

Location:	11p11.2
Sequence:	11; NC_000011.10 (46383789..46391776, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Myopia
Scleral Diseases
Bipolar Disorder
Severe Myopia
Ischemic Stroke
Cardiac Arrhythmia
Ischemia
Infarction
Nerve Degeneration
Heart Failure
Schizophrenia
Diabetes Mellitus

Epilepsy
Major Depressive Disorder
Myocardial Infarction
Heart Diseases
Malignant Neoplasms
Nervousness
Cerebrovascular Accident

Disease

Pathways

Transport
Gene Silencing
Cognition
Pathogenesis
Innervation

Pathways

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

Research Areas

GPCR

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRM4

References

PMID: 3037705 by Bonner T.I., et al. Identification of a family of muscarinic acetylcholine receptor genes.

PMID: 3272174 by Bonner T.I., et al. Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes.