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- Table of Contents
CHRNA5 Antibodies
AND CHRNA5 ELISA kits, CHRNA5 Proteins
Many biological assays use antibodies to detect CHRNA5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNA5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNA5 antibodies...
Designing a Western blot for CHRNA5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CHRNA5 Western Blot GuideCHRNA5 Infographic by Boster Bio
All CHRNA5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # A02359-2
100 μg/vial
Cat # A02359-2
100 μg/vial
Anti-CHRNA5 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M02359-1
100 μl/vial
Cat # M02359-1
100 μl/vial
CHRNA5 Overview
Facts about Neuronal acetylcholine receptor subunit alpha-5.
Neuronal acetylcholine receptor subunit alpha-5 (CHRNA5)
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CHRNA5 |
| Uniprot: | P30532 |
| Entrez: | 1138 |
Family
| Belongs to: |
|---|
| ligand-gated ion channel (TC 1.A.9) family |
Alternative Names
Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5; cholinergic receptor, nicotinic, alpha 5; cholinergic receptor, nicotinic, alpha polypeptide 5; CHRNA5; LNCR2; NACHRA5; neuronal acetylcholine receptor subunit alpha-5; neuronal nicotinic acetylcholine receptor, alpha5 subunit; Nicotinic Acetylcholine R alpha 5; Nicotinic Acetylcholine Ra5
Molecular Weight
Mass (kDA):
53.054 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q25.1 |
| Sequence: | 15; NC_000015.10 (78565520..78595269) |
Subcellular Localizations
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Diseases
- Nicotine Dependence
- Tobacco Use Disorder
- Malignant Neoplasms
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Dysequilibrium Syndrome
- Chronic Obstructive Airway Disease
- Lung Diseases
- Lung Diseases, Obstructive
- Adenocarcinoma
- Epilepsy
Interacting Proteins
- CHRNB2
Pathways
- Pathogenesis
- Localization
- Chromosome Localization
- Cell Proliferation
- Cognition
- Response To Nicotine
- Cell Adhesion
- Habituation
- Prepulse Inhibition
- Catecholamine Secretion
- Fertilization
- Aging
- Cellular Response To Nicotine
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNA5
bosterbio.com/bosterbio-gene-info-cards/CHRNA5
References
PMID: 1542648 by Chini B., et al. Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines.
PMID: 8906617 by Elliott K.J., et al. Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.
6 Publications of Boster CHRNA5 Antibodies & ELISA Kits
- PubMed ID: 10.3390/md18010061, Differential Expression of Nicotine Acetylcholine Receptors Associates with Huma...
- PubMed ID: 10.3390/md17050256, Cervical Cancer Correlates with the Differential Expression of Nicotinic Acetylc...
- PubMed ID: 10.1016/j.freeradbiomed.2021.01.047, Transgenic expression of SOD1 specifically in neurons of Sod1 deficient mice pre...
- PubMed ID: 10.1016/j.ejphar.2019.172674, Identification of nicotinic acetylcholine receptor subunits in different lung ca...
- PubMed ID: 33561489, Su Y,Ahn B,Macpherson PCD,Ranjit R,Claflin DR,Van Remmen H,Brooks SV.Transgenic ...
- PubMed ID: 31963558, Sun Z,Zhangsun M,Dong S,Liu Y,Qian J,Zhangsun D,Luo S.Differential Expression of...
*More publications can be found for each product on its corresponding product page