Protein capicua homolog Antibodies

AND CIC ELISA kits, Protein capicua homolog Proteins

Many biological assays use antibodies to detect Protein capicua homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein capicua homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein capicua homolog antibodies...

We validate the specificity of these antibodies to Protein capicua homolog by testing them on tissues known to express CIC positively and negatively. Browse below to find the CIC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CIC Infographic by Boster Bio

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Anti-CIC Antibody

1 Citations 3 Q&As

Human, Mouse, Rat

ELISA, IHC

$370
Cat # A00385-1
100 μg/vial

Anti-Protein capicua homolog CIC Antibody

Western blot (WB) analysis of CIC polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A00385
100ul

CIC Overview

Facts about Protein capicua homolog.

CIC 3D structure. Source: alphafold

Protein capicua homolog (CIC)

Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.

Gene Information

Human
Gene Name:	CIC
Uniprot:	Q96RK0
Entrez:	23152

Family

Belongs to:

No superfamily

Alternative Names

capicua homolog (Drosophila); KIAA0306capicua (Drosophila) homolog; protein capicua homolog

Molecular Weight

Mass (kDA):
163.82 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (42268537..42295796)

Tissue Specificity

Expressed in fetal brain.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Lupus Erythematosus, Systemic
Arthritis
Neurogenic Urinary Bladder
Rheumatoid Arthritis
Infective Disorder
Hepatitis
Autoimmune Reaction
Glomerulonephritis
Urinary Tract Infection
Kidney Diseases

Urinary Incontinence
Autoimmune Diseases
Carcinoma
Vasculitis
Malignant Paraganglionic Neoplasm
Diabetes Mellitus
Immune Complex Diseases

Interacting Proteins

ATXN1
CENPJ
GOLGA2

Pathways

Pathogenesis
Immune Response
Complement Activation
Localization
Phagocytosis
Transport
Coagulation
Sensitization
Immune Complex Formation
Micturition
Humoral Immune Response
Excretion
Hypersensitivity

Reflex
Secretion
Glomerular Filtration
Cell Proliferation
Aging
Platelet Aggregation
Cell Activation

PTMs

Phosphorylation
Oxidation
Cleavage
Glycosylation
Methylation
Nitration
Demethylation

Carboxylation
Decarboxylation
Citrullination
Dephosphorylation
Biotinylation
Amination
Acetylation

Research Areas

Cancer
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CIC

References

PMID: 12393275 by Lee C.-J., et al. CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons.

PMID: 15981098 by Lee C.-J., et al. CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas.

1 Publications of Boster Protein capicua homolog Antibodies & ELISA Kits

PubMed ID: 10.3969/j.issn.1673-5374.2013.34.008, Mechanisms underlying the beneficial effects of Kaiyu Granule for depression

*More publications can be found for each product on its corresponding product page