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- Table of Contents
CLCNKB Antibodies
AND CLCNKB ELISA kits, CLCNKB Proteins
Many biological assays use antibodies to detect CLCNKB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLCNKB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLCNKB antibodies...
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CLCNKB Overview
Facts about Chloride channel protein ClC-Kb.
Chloride channel protein ClC-Kb (CLCNKB)
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.
May be important in urinary concentrating mechanisms. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CLCNKB |
| Uniprot: | P51801 |
| Entrez: | 1188 |
Family
| Belongs to: |
|---|
| chloride channel (TC 2.A.49) family |
Alternative Names
Chloride channel protein ClC-Kb
Molecular Weight
Mass (kDA):
75.446 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.13 |
| Sequence: | 1; NC_000001.11 (16043782..16057326) |
Tissue Specificity
Expressed predominantly in the kidney.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Bartter syndrome 3 (BARTS3)
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLCNKB
bosterbio.com/bosterbio-gene-info-cards/CLCNKB
References
PMID: 8041726 by Kieferle S., et al. Two highly homologous members of the ClC chloride channel family in both rat and human kidney.
PMID: 8544406 by Takeuchi Y., et al. Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.