CLEC12A Antibodies

AND CLEC12A ELISA kits, CLEC12A Proteins

Many biological assays use antibodies to detect CLEC12A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLEC12A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLEC12A antibodies...

We validate the specificity of these antibodies to CLEC12A by testing them on tissues known to express CLEC12A positively and negatively. Browse below to find the CLEC12A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: LMNTD1

CLEC12A Infographic by Boster Bio

All CLEC12A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CLEC12A Antibody

Western blot analysis of extracts of K-562 cells, using CLEC12A antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A04849
100ul

CLEC12A (NM_138337) Human Over-expression Lysate

CLEC12A Human Over-expression Lysates NM_138337

Human

$628
Cat # LS160364
20 µg, 100 µg

Anti-CLEC12A / CD371 Reference Antibody (tepoditamab)

The purity of Anti-CLEC12A/CD371 Reference Antibody (tepoditamab)is more than 98

Cynomolgus monkey, Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M04849
100 μg

CLEC12A Overview

Facts about C-type lectin domain family 12 member A.

CLEC12A 3D structure. Source: alphafold

C-type lectin domain family 12 member A (CLEC12A)

Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. .

Gene Information

Human
Gene Name:	CLEC12A
Uniprot:	Q5QGZ9
Entrez:	160364

Family

Belongs to:

No superfamily

Alternative Names

CD371; CLEC12A; CLL1; CLL-1; C-type lectin domain family 12, member A; DCAL-2; MICL

Molecular Weight

Mass (kDA):
30.762 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (9951268..9995209)

Tissue Specificity

Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein. Ligand binding leads to internalization.

Diseases

Leukemia
Malignant Paraganglionic Neoplasm
Leukemia, Myelocytic, Acute
Arthritis
Myeloid Leukemia
Rheumatoid Arthritis
Cholangiocarcinoma
Cell Transformation, Neoplastic
Blast Phase
Acute Lymphocytic Leukemia
Autoimmune Diseases
Degenerative Polyarthritis
Immunologic Deficiency Syndromes

Neoplasm, Residual
Autoimmune Reaction
Chromosomal Translocation
Inflammation
Congenital Combined Immunodeficiency
Cytogenetic Abnormality
Dysequilibrium Syndrome

Pathways

Cell Activation
Cytokine Production
Pathogenesis
Cell Proliferation
Receptor Internalization
T Cell Proliferation
T Cell Activation

Glycosylation

PTMs

Glycosylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLEC12A

References

PMID: 15548716 by Bakker A.B.H., et al. C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia.

PMID: 14739280 by Marshall A.S.J., et al. Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes.