CLIC3 Antibodies

AND CLIC3 ELISA kits, CLIC3 Proteins

Many biological assays use antibodies to detect CLIC3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLIC3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLIC3 antibodies...

We validate the specificity of these antibodies to CLIC3 by testing them on tissues known to express CLIC3 positively and negatively. Browse below to find the CLIC3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLIC3 Infographic by Boster Bio

All CLIC3 Products

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Product

Figures

Specificity

Applications

Price

Anti-CLIC3 (F56) Antibody

Western blot (WB) analysis of CLIC3 (F56) pAb at 1:500 dilution
Lane1:3T3-L1 whole cell lysate(40ug)
Lane2:PC12 whole cell lysate(40ug)
Lane3:HCC827 whole cell lysate(40ug)
Lane4:HEK293T whole cell lysate(40ug)
Lane5:H1792 whole cell lysate(40ug)

Human, Mouse, Rat

$405
Cat # A09870-1
100ul

CLIC3 (NM_004669) Human Recombinant Protein

Coomassie blue staining of purified CLIC3 protein

$1249
Cat # PROTO95833
20 µg

CLIC3 (NM_004669) Human Over-expression Lysate

Human

$628
Cat # LS009022
20 µg, 100 µg

Anti-CLIC3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A09870-2
100 μl/vial

CLIC3 Overview

Facts about Chloride intracellular channel protein 3.

CLIC3 3D structure. Source: alphafold

Chloride intracellular channel protein 3 (CLIC3)

Can insert into membranes and form chloride ion channels. May participate in cellular growth control.

Gene Information

Human
Gene Name:	CLIC3
Uniprot:	O95833
Entrez:	9022

Family

Belongs to:

chloride channel CLIC family

Alternative Names

chloride intracellular channel 3; chloride intracellular channel protein 3

Molecular Weight

Mass (kDA):
26.648 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (136994608..136997929, complement)

Tissue Specificity

Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.

Subcellular Localizations

Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).

Diseases

Malignant Neoplasms
Carcinoma
Cell Invasion
Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Neoplasm Metastasis
Cell Transformation, Neoplastic
Complete Hearing Loss
Metastatic Malignant Neoplasm To The Lymph Node
Malignant Neoplasm Of Breast
Tissue Adhesions
Pre-eclampsia

Fetal Growth Retardation
Premature Birth
Disorder Of Pregnancy
Neoplasms
Pancreatic Neoplasm
Renal Cell Carcinoma
Ovarian Neoplasm

Interacting Proteins

EFHC2
POT1

Pathways

Transport
Ion Transport
Induction Of Apoptosis
Chloride Transport
Endocytosis
Localization
Drug Resistance
Cellular Localization
Cell Cycle
Cell Motility

Cell Growth
Regulation Of Cell Growth
Protein Ubiquitination
Autophagy
Oncogenesis

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLIC3

References

PMID: 9880541 by Qian Z., et al. Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel.

PMID: 17027078 by Money T.T., et al. Expression and cellular localisation of chloride intracellular channel 3 in human placenta and fetal membranes.