Clathrin light chain A Antibodies

AND CLTA ELISA kits, Clathrin light chain A Proteins

Many biological assays use antibodies to detect Clathrin light chain A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Clathrin light chain A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Clathrin light chain A antibodies...

We validate the specificity of these antibodies to Clathrin light chain A by testing them on tissues known to express CLTA positively and negatively. Browse below to find the CLTA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Clathrin light chain A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CLTA Western Blot Guide

CLTA Infographic by Boster Bio

All CLTA Products

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Specificity

Applications

Price

Anti-CLTA Antibody Picoband®

Western blot analysis of CLTA using anti-CLTA antibody (A05796-3)

IHC analysis of CLTA using anti-CLTA antibody (A05796-3)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05796-3
100 μg/vial

Clathrin light chain (CLTA) (NM_001833) Human Over-expression Lysate

Clathrin light chain (CLTA) Human Over-expression Lysates NM_001833

Human

$628
Cat # LS001211
20 µg, 100 µg

Clathrin light chain (CLTA) (NM_007096) Human Recombinant Protein

Coomassie blue staining of purified CLTA protein

$1249
Cat # PROTP09496
20 µg

CLTA Overview

Facts about Clathrin light chain A.

CLTA 3D structure. Source: alphafold

Clathrin light chain A (CLTA)

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as component of the TACC3/ch- TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter- microtubule bridge (PubMed:15858577, PubMed:21297582).

Gene Information

Human
Gene Name:	CLTA
Uniprot:	P09496
Entrez:	1211

Family

Belongs to:

clathrin light chain family

Alternative Names

clathrin light chain A; clathrin, light chain A; Lca; light polypeptide (Lca)

Molecular Weight

Mass (kDA):
27.077 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (36190855..36212062)

Subcellular Localizations

Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Cytoplasmic face of coated pits and vesicles. In complex with TACC3 and CKAP5 (forming the TACC3/ch-TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles.

Diseases

Classical Galactosemia
Malignant Neoplasms
Neoplasms
Renal Cell Carcinoma
Glioma
Glioblastoma
Brain Neoplasms

Carcinoma

Interacting Proteins

CALY
CLTC
TACC3

Pathways

Cell Cycle
Mrna Splicing
Translation
Mitosis
Membrane Organization
Metaphase
Conjugation

Anaphase

PTMs

Acetylation

Phosphoprotein

Research Areas

Membrane Trafficking and Chaperones
Membrane Vesicle Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLTA

References

PMID: 3267234 by Jackson A.P., et al. Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.

PMID: 15858577 by Royle S.J., et al. Clathrin is required for the function of the mitotic spindle.