Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 Info At a glance, species: Human
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Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (CMTR2)
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation into the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2).
Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1.
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
|Sequence:||16; NC_000016.10 (71281392..71290178, complement)|