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Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the station when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
|cyclic nucleotide-gated cation channel (TC 1.A.1.5) family|
|Sequence:||2; NC_000002.12 (98346181..98399154)|
Prominently expressed in retina.
Membrane; Multi-pass membrane protein.