Cnot6l Antibodies

AND Cnot6l ELISA kits, Cnot6l Proteins

Many biological assays use antibodies to detect Cnot6l, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cnot6l in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cnot6l antibodies...

We validate the specificity of these antibodies to Cnot6l by testing them on tissues known to express Cnot6l positively and negatively. Browse below to find the Cnot6l antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cnot6l Infographic by Boster Bio

All Cnot6l Products

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CNO6L (CNOT6L) (NM_144571) Human Recombinant Protein

Coomassie blue staining of purified CNOT6L protein

$1062
Cat # PROTQ96LI5
20 µg

CNO6L (CNOT6L) (NM_144571) Human Over-expression Lysate

Human

$960
Cat # LS246175
20 µg, 100 µg

Cnot6l Overview

Facts about CCR4-NOT transcription complex subunit 6-like.

CCR4-NOT transcription complex subunit 6-like (Cnot6l)

Catalytic component of the CCR4-NOT complex that's one of the major cellular mRNA deadenylases and is linked to several cellular processes including majority mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions might be a result of its influence on mRNA expression.

Involved in mRNA decay mediated by the major-protein- coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. Involved in deadenylation-dependent degradation of CDKN1B mRNA.

Gene Information

Mouse
Gene Name:	Cnot6l
Uniprot:	Q8VEG6
Entrez:	231464

Family

Belongs to:

CCR4/nocturin family

Alternative Names

CCR4-NOT transcription complex subunit 6-like

Molecular Weight

Mass (kDA):
63.023 kDA

Genomic Context


Mouse

Location:	5\|5 E3
Sequence:	5;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cnot6l

References

PMID: 20133598 by Suzuki A., et al. NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.

PMID: 21078877 by Clement S.L., et al. Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.