CNTNAP4 Antibodies

AND CNTNAP4 ELISA kits, CNTNAP4 Proteins

Many biological assays use antibodies to detect CNTNAP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CNTNAP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CNTNAP4 antibodies...

We validate the specificity of these antibodies to CNTNAP4 by testing them on tissues known to express CNTNAP4 positively and negatively. Browse below to find the CNTNAP4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNTNAP4 Infographic by Boster Bio

All CNTNAP4 Products

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Anti-CNTP4 CNTNAP4 Antibody

Western Blot analysis of HEK293 lysis, using primary antibody at 1:1000 dilution

Human, Mouse

ELISA, WB

$380
Cat # A10926
100ul

CNTNAP4 Overview

Facts about Contactin-associated protein-like 4.

CNTNAP4 3D structure. Source: alphafold

Contactin-associated protein-like 4 (CNTNAP4)

Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism.

Also participates in the GABAergic system (By similarity). .

Gene Information

Human
Gene Name:	CNTNAP4
Uniprot:	Q9C0A0
Entrez:	85445

Family

Belongs to:

neurexin family

Alternative Names

CASPR4KIAA1763cell recognition protein CASPR4; Cell recognition molecule Caspr4; contactin associated protein-like 4; contactin-associated protein-like 4

Molecular Weight

Mass (kDA):
145.274 kDA

Genomic Context


Human

Location:	16q23.1
Sequence:	16; NC_000016.10 (76277376..76563610)

Subcellular Localizations

Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein. Specifically present within the presynaptic compartment of synapses.

Diseases

Early-stage Breast Carcinoma
Corneal Diseases
Malignant Neoplasms
Neoplasms
Intraocular Pressure Disorder
Malignant Neoplasm Of Breast
Glaucoma, Open-angle
Mammary Neoplasms
Tissue Adhesions

Glaucoma
Primary Open Angle Glaucoma
Carcinoma

Interacting Proteins

TIAM1

Pathways

Cell Adhesion
Cell Cycle
Cell Recognition

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNTNAP4

References

PMID: 20361982 by Shepherd T.R., et al. The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.

PMID: 23395182 by Liu X., et al. The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.