Centriolin Antibodies

AND CNTRL ELISA kits, Centriolin Proteins

Many biological assays use antibodies to detect Centriolin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Centriolin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Centriolin antibodies...

We validate the specificity of these antibodies to Centriolin by testing them on tissues known to express CNTRL positively and negatively. Browse below to find the CNTRL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNTRL Infographic by Boster Bio

All CNTRL Products

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Applications

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Anti-Centriolin CNTRL Antibody

Western blot analysis of extracts of various cell lines, using CNTRL antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A07479
100ul

Anti-CEP110/CNTRL Antibody Picoband®

Western blot analysis of CEP110/CNTRL using anti-CEP110/CNTRL antibody (A07479-1)

Flow Cytometry analysis of HEL cells using anti-CEP110/CNTRL antibody (A07479-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A07479-1
100 μg/vial

CNTRL Overview

Facts about Centriolin.

CNTRL 3D structure. Source: alphafold

Centriolin (CNTRL)

Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle- mediated abscission.

Gene Information

Human
Gene Name:	CNTRL
Uniprot:	Q7Z7A1
Entrez:	11064

Family

Belongs to:

No superfamily

Alternative Names

centriolin

Molecular Weight

Mass (kDA):
268.886 kDA

Genomic Context


Human

Location:	9q33.2
Sequence:	9; NC_000009.12 (121074892..121177610)

Tissue Specificity

Widely expressed with highest levels in testis and trachea.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody, Midbody ring.

Diseases

Pain
Liver Diseases
Knee Pain
Thrombus
Glioma
Degenerative Polyarthritis
Myeloid And Lymphoid Neoplasms With Fgfr1 Rearrangement
Insulin Resistance
Leukemia, Myelocytic, Acute
Nonalcoholic Fatty Liver Disease
Tumor Angiogenesis
Low Grade Glioma

Malignant Neoplasms
Myeloid Leukemia
Neoplasms
Dental Plaque
Dog Diseases
Bacterial Infections
Fatty Liver

Pathways

Cytokinesis
Cell Cycle
Abscission
Transport
Vesicle Targeting
Mitosis
Membrane Fusion
Protein Transport
Localization
Cell Division
Coagulation
Mitotic Spindle Organization

S Phase
Spindle Organization
Interphase
Angiogenesis
Meiosis
Secretion

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNTRL

References

PMID: 10688839 by Guasch G., et al. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33).

PMID: 12732615 by Gromley A., et al. A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase.