COA1 Antibodies

AND COA1 ELISA kits, COA1 Proteins

Many biological assays use antibodies to detect COA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COA1 antibodies...

We validate the specificity of these antibodies to COA1 by testing them on tissues known to express COA1 positively and negatively. Browse below to find the COA1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COA1 Infographic by Boster Bio

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COA1 Overview

Facts about Cytochrome c oxidase assembly factor 1 homolog.

COA1 3D structure. Source: alphafold

Cytochrome c oxidase assembly factor 1 homolog (COA1)

Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes modulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion.

Required for assembly of mitochondrial respiratory chain complex I and complex IV. .

Gene Information

Human
Gene Name:	COA1
Uniprot:	Q9GZY4
Entrez:	55744

Family

Belongs to:

COA1 family

Alternative Names

C7orf44; chromosome 7 open reading frame 44; cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae); FLJ10803; hypothetical protein LOC55744

Molecular Weight

Mass (kDA):
16.694 kDA

Genomic Context


Human

Location:	7p13
Sequence:	7; NC_000007.14 (43608452..43729541, complement)

Subcellular Localizations

Mitochondrion inner membrane; Single-pass membrane protein.

Diseases

Charge Syndrome
Congenital Ocular Coloboma (disorder)
Atresia
Mycobacterium Infections
Nervousness
Paratuberculosis
Choanal Atresia

Goat Diseases
Eye Abnormalities

Pathways

Cell Death
Proteolysis
Pathogenesis

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COA1

References

PMID: 23260140 by Mick D.U., et al. MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation.

PMID: 22356826 by Szklarczyk R., et al. Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase.