COA8 Antibodies

AND COA8 ELISA kits, COA8 Proteins

Many biological assays use antibodies to detect COA8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COA8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COA8 antibodies...

We validate the specificity of these antibodies to COA8 by testing them on tissues known to express COA8 positively and negatively. Browse below to find the COA8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COA8 Infographic by Boster Bio

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COA8 (NM_032374) Human Over-expression Lysate

Human

$628
Cat # LS084334
20 µg, 100 µg

COA8 Overview

Facts about Cytochrome c oxidase assembly factor 8.

COA8 3D structure. Source: alphafold

Cytochrome c oxidase assembly factor 8 (COA8)

Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade.

Gene Information

Human
Gene Name:	COA8
Uniprot:	Q96IL0
Entrez:	84334

Family

Belongs to:

COA8 family

Alternative Names

Cytochrome c oxidase assembly factor 8

Molecular Weight

Mass (kDA):
24.153 kDA

Genomic Context


Human

Location:	14q32.33
Sequence:	14; NC_000014.9 (103562960..103590899)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Mitochondrial complex IV deficiency (MT-C4D)

PTMs

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COA8

References

PMID: 16712791 by Wang A.G., et al. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.

PMID: 30552096 by Signes A., et al. APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS.