Collagen alpha-1(V) chain Antibodies

AND COL5A1 ELISA kits, Collagen alpha-1(V) chain Proteins

Many biological assays use antibodies to detect Collagen alpha-1(V) chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Collagen alpha-1(V) chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Collagen alpha-1(V) chain antibodies...

We validate the specificity of these antibodies to Collagen alpha-1(V) chain by testing them on tissues known to express COL5A1 positively and negatively. Browse below to find the COL5A1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Collagen alpha-1(V) chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the COL5A1 Western Blot Guide

COL5A1 Infographic by Boster Bio

All COL5A1 Products

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Applications

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Anti-COL5A1 (E325) Antibody

Western blot (WB) analysis of COL5A1 (E325) pAb at 1:500 dilution
Lane1:C6 whole cell lysate(40ug)
Lane2:CT26 whole cell lysate(40ug)
Lane3:U-87MG whole cell lysate(40ug)
Lane4:Hela whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of COL5A1 (E325) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A02283-1
100ul

Collagen V alpha1 Colorimetric Cell-Based ELISA Kit

Western blot analysis of the lysates from HUVECcells using Collagen V alpha1 antibody

Human

ELISA

$480
Cat # EKC1130
1 kit, containing one 96-well plate and all necessary reagents

COL5A1 Overview

Facts about Collagen alpha-1(V) chain.

COL5A1 3D structure. Source: alphafold

Collagen alpha-1(V) chain (COL5A1)

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of almost ubiquitous distribution.

Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. .

Gene Information

Human
Gene Name:	COL5A1
Uniprot:	P20908
Entrez:	1289

Family

Belongs to:

fibrillar collagen family

Alternative Names

alpha 1 type V collagen; Collagen 5; collagen alpha-1(V) chain; collagen, type V, alpha 1; Collagen-5; EC 2.7.7.6; EC 6.1.1

Molecular Weight

Mass (kDA):
183.56 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (134641789..134844843)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Ehlers-danlos Syndrome
Joint Laxity
Connective Tissue Diseases
Tendinopathy
Tendon Injuries
Haploinsufficiency
Cicatrix
Cholangiocarcinoma
Corneal Diseases
Tissue Adhesions
Ehlers-danlos Syndrome, Type 2
Tendon Rupture

Nail-patella Syndrome
Contusions
Glaucoma
Inflammation
Dysplasia
Neoplasms

Interacting Proteins

BMP1
FN1
MMP2
PCOLCE
TIMP1

Pathways

Wound Healing
Pathogenesis
Cell Adhesion
Cell Migration
Tissue Development
Cell Cycle
Cell Differentiation
Cell Proliferation
Response To Hypoxia
Angiogenesis
Secretion
Tendon Cell Differentiation
Fibril Organization

Osteoblast Differentiation
Osteoblast Development
Aging
Immune Response
Protein Secretion
Tendon Development
Cell Cycle Arrest

PTMs

Cleavage

Phosphorylation

Reduction

Research Areas

Cell Biology
Cellular Markers
Extracellular Matrix

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL5A1

References

PMID: 2071595 by Takahara K., et al. Complete primary structure of human collagen alpha 1 (V) chain.

PMID: 1722213 by Greenspan D.S., et al. The pro-alpha-1(V) collagen chain: complete primary structure, distribution of expression, and comparison with the pro-alpha-1(XI) collagen chain.