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- Table of Contents
Facts about Protein crumbs homolog 3.
.
| Human | |
|---|---|
| Gene Name: | CRB3 |
| Uniprot: | Q9BUF7 |
| Entrez: | 92359 |

| Belongs to: |
|---|
| No superfamily |

crumbs 3; crumbs homolog 3 (Drosophila); crumbs protein homolog 3; MGC17303
Mass (kDA):
12.854 kDA

| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (6463777..6467221) |
Preferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate.
Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.





PMID: 12527193 by Makarova O., et al. Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1).
PMID: 12771187 by Roh M.H., et al. The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells.