CRHR2 Antibodies

AND CRHR2 ELISA kits, CRHR2 Proteins

Many biological assays use antibodies to detect CRHR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CRHR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CRHR2 antibodies...

We validate the specificity of these antibodies to CRHR2 by testing them on tissues known to express CRHR2 positively and negatively. Browse below to find the CRHR2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CRHR2 Infographic by Boster Bio

All CRHR2 Products

Product

Figures

Specificity

Applications

Price

Anti-CRF-RII (H112) CRHR2 Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A02945
100ul

Anti-CRF-RII CRHR2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A02945-1
100ul

Corticotropin Releasing Factor Receptor 2 (CRHR2) (NM_001883) Human Over-expression Lysate

Human

$628
Cat # LS001395
100 µg

CRHR2 Overview

Facts about Corticotropin-releasing factor receptor 2.

CRHR2 3D structure. Source: alphafold

Corticotropin-releasing factor receptor 2 (CRHR2)

G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN.

Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Gene Information

Human
Gene Name:	CRHR2
Uniprot:	Q13324
Entrez:	1395

Family

Belongs to:

G-protein coupled receptor 2 family

Alternative Names

corticotropin releasing hormone receptor 2; corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2; CRF2; CRF2R; CRFR2; CRF-R2; CRF-R-2; CRFR-2; CRF-RB; CRH2R; CRHR2; CRH-R2; CRH-R-2; HM-CRF

Molecular Weight

Mass (kDA):
47.688 kDA

Genomic Context


Human

Location:	7p14.3
Sequence:	7; NC_000007.14 (30649406..30700103, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Anxiety Disorders
Pituitary Diseases
Physiological Stress
Depressive Disorder
Obesity
Inflammation
Panic Disorder
Cancer Patients And Suicide And Depression
Nervousness
Major Depressive Disorder
Carcinoma

Colitis
Disease Of Adrenal Medulla
Hypoxia
Tumor Angiogenesis
Malignant Neoplasms
Stress, Psychological

Pathways

Response To Stress
Secretion
Transport
Feeding Behavior
Endocytosis
Inflammatory Response
Localization
Angiogenesis
Corticosterone Secretion
Cell Adhesion
Progesterone Secretion
Habituation
Aging

Immune Response
Tube Formation
Hypersensitivity
Reverse Transcription
Conditioned Taste Aversion
Estrus
Luteolysis

PTMs

Phosphorylation

Reduction

Cleavage

Research Areas

GPCR
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRHR2

References

PMID: 8536644 by Liaw C.W., et al. Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid.

PMID: 9717834 by Kostich W.A., et al. Molecular identification and analysis of a novel human corticotropin- releasing factor (CRF) receptor: the CRF2gamma receptor.