CRLF1 Antibodies

AND CRLF1 ELISA kits, CRLF1 Proteins

Many biological assays use antibodies to detect CRLF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CRLF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CRLF1 antibodies...

We validate the specificity of these antibodies to CRLF1 by testing them on tissues known to express CRLF1 positively and negatively. Browse below to find the CRLF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CRLF1 Infographic by Boster Bio

All CRLF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-CRLF1 Antibody

Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night

Human, Mouse

ELISA, WB

$380
Cat # A06784
100ul

CRLF1 (NM_004750) Human Over-expression Lysate

Human

$628
Cat # LS009244
20 µg, 100 µg

CRLF1 Overview

Facts about Cytokine receptor-like factor 1.

CRLF1 3D structure. Source: alphafold

Cytokine receptor-like factor 1 (CRLF1)

Cytokine receptor subunit, maybe playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development.

Gene Information

Human
Gene Name:	CRLF1
Uniprot:	O75462
Entrez:	9244

Family

Belongs to:

type I cytokine receptor family

Alternative Names

CISS1; CISScytokine type 1 receptor CRLP-1; CLF; CLF1; CLF-1; CLF-1class I cytokine receptor; CRLF1; CRLF-1; cytokine receptor-like factor 1; Cytokine-like factor 1; NR6; zcytor5

Molecular Weight

Mass (kDA):
46.302 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (18593237..18606799, complement)

Tissue Specificity

Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung.

Subcellular Localizations

Secreted.

Diseases

Congenital Camptodactyly
Scoliosis, Unspecified
Sudden Death
Increased Sweating
Trismus
Stuve-wiedemann Syndrome
Kyphoscoliosis Deformity Of Spine
Degenerative Polyarthritis
Autonomic Nervous System Disorders
Inflammatory Bowel Diseases
Lung Diseases

De Novo Mutation
Sweat Gland Diseases
Opisthotonus
Dysplasia
Fibrosis
Usual Interstitial Pneumonitis

Pathways

Pathogenesis
Cell Adhesion
Cell Division
Membrane Depolarization
Translation
Cell Differentiation
Dedifferentiation
Neurogenesis

Developmental Growth
Secretion

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRLF1

References

PMID: 9686600 by Elson G.C.A., et al. Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family.

PMID: 10966616 by Elson G.C.A., et al. CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex.