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C-X-C motif chemokine 6 Antibodies
AND CXCL6 ELISA kits, C-X-C motif chemokine 6 Proteins
Many biological assays use antibodies to detect C-X-C motif chemokine 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-X-C motif chemokine 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-X-C motif chemokine 6 antibodies...
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CXCL6 Infographic by Boster Bio
All CXCL6 Products
Product
Figures
Specificity
Applications
Price
Human CXCL6/GCP2 ELISA Kit PicoKine®
4 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0359
96 wells/kit, with removable strips.
Cat # EK0359
96 wells/kit, with removable strips.
Human
$250
Cat # PROTP80162
5ug, 20ug, 1mg
Cat # PROTP80162
5ug, 20ug, 1mg
Human
ELISA
$499
Cat # FEK0359
96 wells/kit, with removable strips.
Cat # FEK0359
96 wells/kit, with removable strips.
CXCL6 Overview
Facts about C-X-C motif chemokine 6.
C-X-C motif chemokine 6 (CXCL6)
Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2).
Besides its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram- negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). .
Gene Information
| Human | |
|---|---|
| Gene Name: | CXCL6 |
| Uniprot: | P80162 |
| Entrez: | 6372 |
Family
| Belongs to: |
|---|
| intercrine alpha (chemokine CxC) family |
Alternative Names
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); Chemokine alpha 3; CKA-3Granulocyte chemotactic protein 2; CXCL6; GCP-2; GCP2member 6 (granulocytechemotactic protein 2); GCP-2Small-inducible cytokine B6; Small inducible cytokine subfamily B (Cys-X-Cys), member b
Molecular Weight
Mass (kDA):
11.897 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (73836678..73838760) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Neoplasms
- Tumor Angiogenesis
- Malignant Neoplasms
- Inflammatory Response
- Carcinoma
- Cholangiocarcinoma
- Neoplasm Metastasis
- Tissue Adhesions
- Pathologic Neovascularization
- Arthritis
- Osteosarcoma
Interacting Proteins
- CCL5
- CXCL12
- PF4
Pathways
- Chemotaxis
- Angiogenesis
- Pathogenesis
- Secretion
- Inflammatory Response
- Neutrophil Chemotaxis
- Immune Response
- Cell Adhesion
- Chemokine Production
- Cell Proliferation
- Cell Migration
- Innate Immune Response
- Neutrophil Activation
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXCL6
bosterbio.com/bosterbio-gene-info-cards/CXCL6
References
PMID: 9164944 by Rovai L.E., et al. Cloning and characterization of the human granulocyte chemotactic protein-2 gene.
PMID: 9057843 by Froyen G., et al. Cloning, bacterial expression and biological characterization of recombinant human granulocyte chemotactic protein-2 and differential expression of granulocyte chemotactic protein-2 and epithelial cell- derived neutrophil activating peptide-78 mRNAs.
4 Publications of Boster C-X-C motif chemokine 6 Antibodies & ELISA Kits
- PubMed ID: 10.3389/fphar.2019.00307, Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarc...
- PubMed ID: 10.1177/2472555216685519, Identification and Validation of Gene Expression Patterns in Cystitis Glandulari...
- PubMed ID: 33167688, Li L, Man J, Zhao L. Hypoxia-CXCL6 axis affects arteriolar niche remodeling in a...
- PubMed ID: 30774371, miRNA-101-5p inhibits the growth and aggressiveness of NSCLC cells through targe...
*More publications can be found for each product on its corresponding product page