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- Table of Contents
Interleukin-8 Antibodies
AND CXCL8 ELISA kits, Interleukin-8 Proteins
Many biological assays use antibodies to detect Interleukin-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-8 antibodies...
Designing a Western blot for Interleukin-8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CXCL8 Western Blot GuideCXCL8 Infographic by Boster Bio
All CXCL8 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$399
Cat # EK0413
96 wells/kit, with removable strips.
Cat # EK0413
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0413
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ0413
For 5 plates, 96 wells each, reagents only, plates are not included
Human
ELISA
$499
Cat # FEK0413
96 wells/kit, with removable strips.
Cat # FEK0413
96 wells/kit, with removable strips.
Human
ELISA
$519
Cat # HSEK0413
96 wells/kit, with removable strips.
Cat # HSEK0413
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00423-2
100 μg
Cat # M00423-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00423-4
100 μg
Cat # M00423-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00423-3
100 μg
Cat # M00423-3
100 μg
Swine
Cell Culture
$154
Cat # PROTP26894-1
5ug,20ug
Cat # PROTP26894-1
5ug,20ug
Human
Cell Culture
$77
Cat # PROTP10145-7
5ug,20ug,100ug
Cat # PROTP10145-7
5ug,20ug,100ug
CXCL8 Overview
Facts about Interleukin-8.
Interleukin-8 (CXCL8)
IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. Additionally it is involved in neutrophil activation.
It's released from several cell types in response to an inflammatory stimulus. IL-8(6-77) includes a 5-10-fold higher action on neutrophil activation, IL-8(5-77) has increased action on neutrophil activation and IL-8(7-77) has a greater affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Gene Information
| Human | |
|---|---|
| Gene Name: | CXCL8 |
| Uniprot: | P10145 |
| Entrez: | 3576 |
Family
| Belongs to: |
|---|
| intercrine alpha (chemokine CxC) family |
Alternative Names
3-10C; AMCF-I; C-X-C motif chemokine 8; CXCL8; CXCL8SCYB8; Emoctakin; GCP1; GCP-1TSG-1; IL8; IL-8; interleukin 8; K60; LAI; LECT; LUCT; LYNAP; MDNCF; MDNCFb-ENAP; member 8; MONAP; MONAPGCP1; NAF; NAP1; NAP-1NAP1; NCF; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; TCF; TSG1
Molecular Weight
Mass (kDA):
11.098 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (73740569..73743716) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Malignant Neoplasms
- Inflammatory Response
- Neoplasms
- Tissue Adhesions
- Carcinoma
- Tumor Angiogenesis
- Lung Diseases
- Infective Disorder
- Fibrosis
- Asthma
- Atherosclerosis
- Chronic Obstructive Airway Disease
Interacting Proteins
- CXCR2
- PF4
- TNFAIP6
Pathways
- Secretion
- Pathogenesis
- Inflammatory Response
- Immune Response
- Angiogenesis
- Cytokine Production
- Cell Proliferation
- Chemotaxis
- Innate Immune Response
- Cell Activation
- Cell Adhesion
- Cytokine Secretion
- Cell Growth
PTMs
- Phosphorylation
- Acetylation
- Methylation
- Cleavage
- Oxidation
- Reduction
- Nitration
- Glycosylation
- Carboxylation
Research Areas
- Angiogenesis
- Cancer
- Chemokines and Cytokines
- Cytokine Research
- Immunology
- Innate Immunity
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXCL8
bosterbio.com/bosterbio-gene-info-cards/CXCL8
References
PMID: 2953813 by Schmid J., et al. Induction of mRNA for a serine protease and a beta-thromboglobulin- like protein in mitogen-stimulated human leukocytes.
PMID: 3260265 by Matsushima K., et al. Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.
180 Publications of Boster Interleukin-8 Antibodies & ELISA Kits
- PubMed ID: PMID:33312360, The effect of the surgical microscope on the outcome of root scaling
- PubMed ID: PMID:31966515, Identification of genes involved in enterovirus 71 infected SK-N-SH cells
- PubMed ID: PMID:26191144, Inflammatory response of macrophages cultured with Helicobacter pylori strains w...
- PubMed ID: 10.4187/respcare.03519, Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD
- PubMed ID: 10.4103/2321-3868.137604, Evaluation of optimized continuous venovenous hemodiafiltration therapy efficien...
- PubMed ID: 10.4103/1673-5374.139461, Neuroprotective effect of pretreatment with ganoderma lucidum in cerebral ischem...
- PubMed ID: 10.3892/ijo.2019.4775, Inflammatory responses induced by Helicobacter pylori on the carcinogenesis of g...
- PubMed ID: 10.3892/etm.2020.9204, Mechanisms of the lipopolysaccharide‑induced inflammatory response in alveolar...
- PubMed ID: 10.3892/etm.2019.7617, Differential clinical benefits of continuous blood purification treatment in cri...
- PubMed ID: 10.3892/etm.2016.3680, Randomized, double-blind, placebo-controlled superiority trial of the Yiqigubiao...
- PubMed ID: 10.3892/etm.2016.3157, Characteristics of CD4+CD25+Foxp3+ regulatory T cells in patients with multiple ...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2011.04.021, Flagellin ofPseudomonas aeruginosainduces transforming growth factor beta 1 expr...
- PubMed ID: 10.3727/096504015X14496932933610, ERK Signaling Pathway Is Involved in HPV-16 E6 but not E7 Oncoprotein-Induced HI...
- PubMed ID: 10.3390/pharmaceutics13050737, Chondroitin Sulfate in USA Dietary Supplements in Comparison to Pharma Grade Pro...
- PubMed ID: 10.3390/ijms17030385, C/EBP β Mediates Endoplasmic Reticulum Stress Regulated Inflammatory Response a...
- PubMed ID: 10.3389/fphys.2020.00441, Exosomal MicroRNA-320a Derived From Mesenchymal Stem Cells Regulates Rheumatoid ...
- PubMed ID: 10.3389/fmicb.2020.566473, Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strai...
- PubMed ID: 10.3389/fimmu.2021.637659, Activation of Toll-Like Receptor 7 Signaling Pathway in Primary Sjögrens Syndro...
- PubMed ID: 10.3103/S0095452717030124, RETRACTED ARTICLE: Sodium ferulate inhibits high-fat diet-induced inflammatory f...
- PubMed ID: 10.2217/bmm-2019-0124, Interleukins and miRNAs intervene in the early stages of diabetic kidney disease...
- PubMed ID: 10.2147/OTT.S161760, IL-8 regulates the stemness properties of cancer stem cells in the small-cell lu...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page